[HTML][HTML] Epigenetic plasticity: a central regulator of epithelial-to-mesenchymal transition in cancer

U Bedi, VK Mishra, D Wasilewski, C Scheel… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Tumor metastasis is the major cause of mortality and morbidity in most solid cancers. A
growing body of evidence suggests that the epithelial-to-mesenchymal transition (EMT) …

Epigenetic regulation of epithelial–mesenchymal transition

L Sun, J Fang - Cellular and molecular life sciences, 2016 - Springer
Epithelial–mesenchymal transition (EMT) is an essential process for morphogenesis and
organ development which reversibly enables polarized epithelial cells to lose their epithelial …

[HTML][HTML] Epigenetic regulation of epithelial to mesenchymal transition in the cancer metastatic cascade: implications for cancer therapy

QL Liu, M Luo, C Huang, HN Chen, ZG Zhou - Frontiers in Oncology, 2021 - frontiersin.org
Metastasis is the end stage of cancer progression and the direct cause of most cancer-
related deaths. The spreading of cancer cells from the primary site to distant organs is a …

[HTML][HTML] Epigenetic control of epithelial-mesenchymal-transition in human cancer

T Kiesslich, M Pichler… - … and clinical oncology, 2013 - spandidos-publications.com
Abstract Development and tissue homeostasis as well as carcinogenesis share the
evolutionary conserved process of epithelial-mesenchymal transition (EMT). EMT enables …

EMT, cell plasticity and metastasis

CL Chaffer, BP San Juan, E Lim… - Cancer and Metastasis …, 2016 - Springer
Carcinoma cells that are induced to suppress their epithelial features and upregulate
mesenchymal gene expression programs acquire traits that promote an invasive and …

[HTML][HTML] Epigenetic modification regulates tumor progression and metastasis through EMT

T Tan, P Shi, MN Abbas, Y Wang… - International …, 2022 - spandidos-publications.com
Epigenetics is the study of heritable molecular determinants that are independent of
phenotypic features. The epigenetic features include DNA methylation, histone …

Epigenetic control of epithelial-to-mesenchymal transition and cancer metastasis

Y Wang, Y Shang - Experimental cell research, 2013 - Elsevier
Epithelial–mesenchymal transition (EMT) is vital for morphogenesis during embryonic
development and is also critical for the conversion of early stage tumors into invasive …

[HTML][HTML] Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications

SJ Serrano-Gomez, M Maziveyi, SK Alahari - Molecular cancer, 2016 - Springer
The epithelial to mesenchymal transition (EMT) is a biological process in which a non-motile
epithelial cell changes to a mesenchymal phenotype with invasive capacities. This …

[HTML][HTML] Unresolved complexity in the gene regulatory network underlying EMT

DP Lavin, VK Tiwari - Frontiers in oncology, 2020 - frontiersin.org
Epithelial to mesenchymal transition (EMT) is the process whereby a polarized epithelial cell
ceases to maintain cell-cell contacts, loses expression of characteristic epithelial cell …

[HTML][HTML] Tackle epithelial-mesenchymal transition with epigenetic drugs in cancer

B Dong, Z Qiu, Y Wu - Frontiers in Pharmacology, 2020 - frontiersin.org
Epithelial-mesenchymal Transition (EMT) is a de-differentiation process in which epithelial
cells lose their epithelial properties to acquire mesenchymal features. EMT is essential for …