The role of adenosine receptors in mood and anxiety disorders
D van Calker, K Biber, K Domschke… - Journal of …, 2019 - Wiley Online Library
Adenosine receptor subtypes, first described 40 years ago, are known to regulate diverse
biological functions and have a role in various conditions, such as cerebral and cardiac …
biological functions and have a role in various conditions, such as cerebral and cardiac …
Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders
The interest on targeting adenosine A2A receptors in the realm of psychiatric diseases first
arose based on their tight physical and functional interaction with dopamine D2 receptors …
arose based on their tight physical and functional interaction with dopamine D2 receptors …
Adenosine A2A receptors in psychopharmacology: modulators of behavior, mood and cognition
HY Shen, JF Chen - Current neuropharmacology, 2009 - ingentaconnect.com
The adenosine A2A receptor (A2AR) is in the center of a neuromodulatory network affecting
a wide range of neuropsychiatric functions by interacting with and integrating several …
a wide range of neuropsychiatric functions by interacting with and integrating several …
[HTML][HTML] Normal and abnormal functions of adenosine receptors in the central nervous system revealed by genetic knockout studies
CJ Wei, W Li, JF Chen - Biochimica et biophysica acta (BBA) …, 2011 - Elsevier
Endogenous adenosine is a widely distributed upstream regulator of a broad spectrum of
neurotransmitters, receptors, and signaling pathways that converge to contribute to the …
neurotransmitters, receptors, and signaling pathways that converge to contribute to the …
Involvement of adenosine A2A receptors in depression and anxiety
K Yamada, M Kobayashi, T Kanda - International Review of Neurobiology, 2014 - Elsevier
When administered to normal healthy patients, a nonselective adenosine A 1/A 2A
antagonist, caffeine, tended to improve anxiety and depression at low doses and to …
antagonist, caffeine, tended to improve anxiety and depression at low doses and to …
Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety
Adenosine A2A receptors (A2AR) are a sub-type of receptors enriched in basal ganglia,
activated by the neuromodulator adenosine, which interact with dopamine D2 receptors …
activated by the neuromodulator adenosine, which interact with dopamine D2 receptors …
Adenosine A2A receptor antagonists are potential antidepressants: evidence based on pharmacology and A2A receptor knockout mice
ME Yacoubi, C Ledent, M Parmentier… - British journal of …, 2001 - Wiley Online Library
Adenosine, an ubiquitous neuromodulator, and its analogues have been shown to produce
'depressant'effects in animal models believed to be relevant to depressive disorders, while …
'depressant'effects in animal models believed to be relevant to depressive disorders, while …
Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry: implications for drug addiction, sleep and pain
S Ferré, I Diamond, SR Goldberg, L Yao… - Progress in …, 2007 - Elsevier
Adenosine A2A receptors localized in the dorsal striatum are considered as a new target for
the development of antiparkinsonian drugs. Co-administration of A2A receptor antagonists …
the development of antiparkinsonian drugs. Co-administration of A2A receptor antagonists …
Central adenosine A2A receptors: an overview
JL Moreau, G Huber - Brain research reviews, 1999 - Elsevier
Recent advances in molecular biology, biochemistry, cell biology and behavioral
pharmacology together with the development of more selective ligands to the various …
pharmacology together with the development of more selective ligands to the various …
Adenosine receptors in neuropsychiatric disorders: fine regulators of neurotransmission and potential therapeutic targets
Adenosine exerts an important role in the modulation of central nervous system (CNS)
activity. Through the interaction with four G-protein coupled receptor (GPCR) subtypes …
activity. Through the interaction with four G-protein coupled receptor (GPCR) subtypes …