Drugs and nanoformulations for the management of Leishmania infection: a patent and literature review (2015-2022)

M Verdan, I Taveira, F Lima, F Abreu… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Leishmaniasis is an important disease caused by parasites of the Leishmania.
Due to the urgent need for financial incentives and research and development of new anti …

Therapeutic efficacy of artemisinin-loaded nanoparticles in experimental visceral leishmaniasis

MY Want, M Islamuddin, G Chouhan, HA Ozbak… - Colloids and Surfaces B …, 2015 - Elsevier
Visceral leishmaniasis (VL) is a fatal vector-borne parasitic syndrome attributable to the
protozoa of the Leishmania donovani complex. The available chemotherapeutic options are …

Drug delivery systems for the topical treatment of cutaneous leishmaniasis

G Carneiro, MG Aguiar, AP Fernandes… - Expert opinion on drug …, 2012 - Taylor & Francis
Introduction: The parenteral administration of pentavalent antimonials for the treatment of all
forms of leishmaniasis, including cutaneous leishamniasis (CL), has several limitations …

Overcoming multi‐resistant leishmania treatment by nanoencapsulation of potent antimicrobials

SSC Oliveira, CS Ferreira… - Journal of Chemical …, 2021 - Wiley Online Library
Leishmaniasis corresponds to a group of neglected tropical diseases caused by flagellated
protozoa belonging to the Leishmania genus. This widely spread illness is found in over 90 …

Drug Targeting to Macrophages With Solid Lipid Nanoparticles Harboring Paromomycin: an In Vitro Evaluation Against L. major and L. tropica

MH Kharaji, D Doroud, T Taheri, S Rafati - Aaps Pharmscitech, 2016 - Springer
Leishmaniasis is a worldwide disease that leads to high mortality and morbidity in human
populations. Today, leishmaniasis is managed via drug therapy. The drugs that are already …

Recent advances and new strategies on leishmaniasis treatment

BM Roatt, JM de Oliveira Cardoso… - Applied Microbiology …, 2020 - Springer
Leishmaniasis is one of the most important tropical neglected diseases according to the
World Health Organization. Even after more than a century, we still have few drugs for the …

Macrophage specific drug delivery in experimental leishmaniasis

MK Basu, S Lala - Current molecular medicine, 2004 - ingentaconnect.com
Macrophage-specific delivery systems are the subject of much interest nowadays, because
of the fact that macrophages act as host cells for many parasites and bacteria, which give …

Nanoparticles as multifunctional devices for the topical treatment of cutaneous leishmaniasis

E Moreno, J Schwartz, C Fernandez… - Expert Opinion on …, 2014 - Taylor & Francis
Introduction: Cutaneous and mucocutaneous leishmaniasis are major tropical skin diseases.
Topical treatment is currently limited to the least severe forms of cutaneous leishmaniasis …

New approaches from nanomedicine for treating leishmaniasis

V Gutiérrez, AB Seabra, RM Reguera… - Chemical Society …, 2016 - pubs.rsc.org
Leishmaniasis, a vector-borne disease caused by obligate intramacrophage protozoa,
threatens 350 million people in 98 countries around the world. There are already 12 million …

Recent strategies for the development of oral medicines for the treatment of visceral leishmaniasis

ML de Souza, LA Gonzaga da Costa… - Drug Development …, 2020 - Wiley Online Library
Considered prevalent in many countries on five continents, especially in low‐income
regions, leishmaniasis is a neglected tropical disease classified by World Health …