Development, characterization, and anti-leishmanial activity of topical amphotericin B nanoemulsions

AP dos Santos Matos, DCDXP Lopes… - Drug Delivery and …, 2020 - Springer
Leishmaniasis is a neglected infectious disease caused by protozoan parasites from
Leishmania genus species, affecting millions of people, in several countries. The current …

Nanoarchitectures for neglected tropical protozoal diseases: challenges and state of the art

S Pund, A Joshi - Nano-and microscale drug delivery systems, 2017 - Elsevier
Leishmaniasis and trypanosomiasis (Chagas disease and African sleeping sickness) are
potentially lethal, tropical neglected diseases. These vector-borne protozoal diseases …

Delivery strategies for antiparasitics

O Kayser, AF Kiderlen - Expert Opinion on Investigational Drugs, 2003 - Taylor & Francis
Optimisation of drug carrier systems and drug delivery strategies that take into account the
peculiarities of individual infectious agents and diseases are key elements of modern drug …

[PDF][PDF] Biological targeting drug delivery in control of Leishmaniasis

P Roy, S Das, RG Auddy, A Mukherjee - J Cell Anim Biol, 2012 - academicjournals.org
Leishmaniasis is a neglected tropical disease caused by a protozoan parasite of the genus
Leishmania. Visceral leishmaniasis is the most severe type and is transmitted by the …

Chitosan-based nanomaterials as valuable sources of anti-leishmanial agents: a systematic review

HI AlMohammed, A Khudair Khalaf, A E. Albalawi… - Nanomaterials, 2021 - mdpi.com
Background: The current chemotherapy agents against various forms of leishmaniasis have
some problems and side effects, including high toxicity, high cost, and the emergence of …

Nanospheres encapsulating anti-leishmanial drugs for their specific macrophage targeting, reduced toxicity, and deliberate intracellular release

AK Shukla, S Patra, VK Dubey - Vector-Borne and Zoonotic …, 2012 - liebertpub.com
The current work focuses on the study of polymeric, biodegradable nanoparticles (NPs) for
the encapsulation of doxorubicin and mitomycin C (anti-leishmanial drugs), and their …

The designing of a gel formulation with chitosan polymer using liposomes as nanocarriers of amphotericin B for a non-invasive treatment model of cutaneous …

N GÜRBÜZ ÇOLAK, EÖ ÇETİN UYANIKGİL, Y Özbel… - Acta Parasitologica, 2022 - Springer
Purpose Leishmaniasis is a disease caused by different Leishmania spp., which are
transmitted to humans by a bite of infected female sand flies. Cutaneous leishmaniasis (CL …

Development of antileishmanial lipid nanocomplexes

TTH Pham, C Gueutin, M Cheron, S Abreu… - Biochimie, 2014 - Elsevier
Visceral leishmaniasis is a life-threatening disease that affects nearly a million people every
year. The emergence of Leishmania strains resistant to existing drugs complicates its …

Coalition of biological agent (melatonin) with chemotherapeutic agent (amphotericin B) for combating visceral leishmaniasis via oral administration of modified solid …

S Parvez, G Yadagiri, K Arora, A Javaid… - ACS Biomaterials …, 2021 - ACS Publications
In this study, 2-hydroxypropyl-β-cyclodextrin (HPβCD) grafted solid lipid nanoparticle (SLN)-
based bioconjugate was synthesized and used for administering a combination of melatonin …

In vitro evaluation of bisnaphthalimidopropyl derivatives loaded into pegylated nanoparticles against Leishmania infantum protozoa

SC Lima, V Rodrigues, J Garrido, F Borges… - International journal of …, 2012 - Elsevier
Bisnaphthalimidopropyl (BNIP) derivatives have recently been shown to have potential as
antileishmanial agents. However, these compounds have some drawbacks, including their …