Liposomal formulations in the pharmacological treatment of leishmaniasis: a review

V Ortega, S Giorgio, E de Paula - Journal of liposome research, 2017 - Taylor & Francis
Conventional chemotherapy for leishmaniasis includes considerably toxic drugs and reports
of drug-resistance are not uncommon. Liposomal encapsulated drugs appear as an option …

[HTML][HTML] Antileishmanial activity of amphotericin B-loaded-PLGA nanoparticles: an overview

E Palma, A Pasqua, A Gagliardi, D Britti, M Fresta… - Materials, 2018 - mdpi.com
In recent decades, nanotechnology has made phenomenal strides in the pharmaceutical
field, favouring the improvement of the biopharmaceutical properties of many active …

Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment

JG Galvão, RL Santos, ARST Silva, JS Santos… - European Journal of …, 2020 - Elsevier
Leishmaniasis are a group of neglected infectious diseases caused by protozoa of the
genus Leishmania with distinct presentations. The available leishmaniasis treatment options …

[HTML][HTML] Nanoparticles: New agents toward treatment of leishmaniasis

A Nafari, K Cheraghipour, M Sepahvand… - Parasite epidemiology …, 2020 - Elsevier
Leishmaniasis is a widespread disease that causes 20,000 to 30,000 deaths annually,
making it a major health problem in endemic areas. Because of low-performance …

Novel targeting using nanoparticles: an approach to the development of an effective anti-leishmanial drug-delivery system

TG Ribeiro, MA Chávez-Fumagalli… - International journal …, 2014 - Taylor & Francis
The study reported here aimed to develop an optimized nanoparticle delivery system for
amphotericin B (AmpB) using a polyelectrolyte complexation technique. For this, two …

Delivery systems for Leishmania vaccine development

E Gholami, F Zahedifard, S Rafati - Expert review of vaccines, 2016 - Taylor & Francis
Leishmaniasis is a neglected disease and is endemic in tropical and sub-tropical areas
worldwide. Lifelong immunity after recovery indicates that vaccination could be a promising …

Evaluation of in vitro and in vivo Efficacy of a Novel Amphotericin B-Loaded Nanostructured Lipid Carrier in the Treatment of Leishmania braziliensis Infection

J Rebouças-Silva, MC Tadini… - International Journal …, 2020 - Taylor & Francis
Background Leishmaniasis is a neglected disease, and the current therapeutic arsenal for
its treatment is seriously limited by high cost and toxicity. Nanostructured lipid carriers …

Formulation, characterization and in vitro anti-leishmanial evaluation of amphotericin B loaded solid lipid nanoparticles coated with vitamin B12-stearic acid conjugate

A Singh, G Yadagiri, S Parvez, OP Singh… - Materials Science and …, 2020 - Elsevier
Despite the advancement of new anti-leishmanials, amphotericin B (AmB) prevails as one of
the most potent agent in the treatment of visceral leishmaniasis (VL), a neglected tropical …

Non-polymeric nano-carriers in HIV/AIDS drug delivery and targeting

U Gupta, NK Jain - Advanced drug delivery reviews, 2010 - Elsevier
Development of an effective drug delivery approach for the treatment of HIV/AIDS is a global
challenge. The conventional drug delivery approaches including Highly Active Anti …

[HTML][HTML] Current and promising novel drug candidates against visceral leishmaniasis

RM Reguera, Y Pérez-Pertejo… - Pure and Applied …, 2019 - degruyter.com
Leishmaniasis is a group of zoonotic diseases caused by a trypanosomatid parasite mostly
in impoverished populations of low-income countries. In their different forms, leishmaniasis …