The effect of off-label use of reduced-dose direct oral anticoagulants therapy in the treatment of pulmonary embolism comparable to standard-dose therapy

S Yamazoe, H Imai, Y Ogawa, N Kano, Y Murase… - Heart and Vessels, 2024 - Springer
Direct oral anticoagulants (DOACs) have been shown to be effective and safe in preventing
pulmonary embolism recurrence. In this single-center retrospective observational study, we …

Non-recommended dosing of direct oral anticoagulants in the treatment of acute pulmonary embolism is related to an increased rate of adverse events

R Chopard, G Serzian, S Humbert, N Falvo… - Journal of Thrombosis …, 2018 - Springer
Dose adjustment of direct oral anticoagulants (DOACs) is not required in the setting of acute
PE treatment according to the manufacturer's labelling, beyond the contraindication in …

Prescription patterns of direct oral anticoagulants in pulmonary embolism: A prospective multicenter French registry

R Chopard, JN Andarelli, S Humbert, N Falvo… - Thrombosis …, 2019 - Elsevier
Background Data regarding the use of direct oral anticoagulants (DOACs) for the treatment
of acute pulmonary embolism (PE) are sparse. We conducted a prospective multicentre …

Reducing length of stay with the direct oral anti-coagulants in low and intermediate risk pulmonary embolism: a single center experience

J Filopei, EE Bondarsky, M Ehrlich, M Islam… - Journal of Thrombosis …, 2020 - Springer
Direct oral anti-coagulants (DOACs) reduce hospital length-of-stay (LOS) in patients with
acute pulmonary embolism (PE) in clinical trials. There is a paucity of literature describing …

Retrospective analysis of direct-acting oral anticoagulants (DOACs) initiation timing and outcomes after thrombolysis in high-and intermediate-risk pulmonary …

A Wolfe, A Phillips, DM Tierney… - Clinical and Applied …, 2023 - journals.sagepub.com
Direct-acting oral anticoagulants (DOACs) are prescribed in the treatment of venous
thromboembolism, including pulmonary embolism (PE). Evidence is limited regarding the …

Efficacy and safety of direct oral anticoagulants after pulmonary embolism: a meta-analysis

MC Vedovati, C Becattini… - International …, 2014 - internationaljournalofcardiology.com
Direct oral anticoagulants are as effective as conventional anticoagulant treatment after
pulmonary embolism with a reduction in major bleeding when the single-drug approach was …

Risk stratification and management of acute pulmonary embolism

C Becattini, G Agnelli - Hematology 2014, the American Society …, 2016 - ashpublications.org
The clinical management of patients with acute pulmonary embolism is rapidly changing
over the years. The widening spectrum of clinical management strategies for these patients …

Early prescription of direct oral anticoagulant for the treatment of intermediate-high risk pulmonary embolism: a multi-center, observational cohort study

R Chopard, M Badoz, C Eveno, F Ecarnot, N Falvo… - Thrombosis …, 2020 - Elsevier
Objectives The safety and efficacy of direct oral anticoagulants (DOACs) in intermediate-
high risk pulmonary embolism (PE) are unknown. The aims of the present study were to …

Administration of Direct Oral Anticoagulant Immediately after Unfractionated Heparin Bolus for the Treatment of Intermediate–High-Risk Pulmonary Thromboembolism

N Hara, K Watanabe, R Miyazaki… - Annals of Vascular …, 2020 - jstage.jst.go.jp
Objective: This study aims to evaluate the efficacy and safety of direct oral anticoagulants
(DOACs) after unfractionated heparin (UFH) bolus for the treatment of intermediate–high-risk …

Differences between activities of coagulation factors after one month of therapy with different direct oral anticoagulant in pulmonary embolism patients

J Dzudovic, B Dzudovic, V Subota… - Journal of clinical …, 2019 - Wiley Online Library
What is known and Objective Direct oral anticoagulants (DOACs) are frequently used for the
treatment of pulmonary embolism (PE), but both clinical and laboratory data comparing their …