Objective To determine whether aerobic exercise training+ weight loss (AEX+ WL) would
affect the expression of myostatin and its relationship with insulin sensitivity in a longitudinal …

Myostatin mutations in mice and cattle are associated with increased muscularity,
suggesting that myostatin is a negative regulator of skeletal muscle mass. To test the …

BACKGROUND: Myostatin is a recently discovered member of the TGF-b superfamily of
genes. It is expressed in skeletal muscle and believed to suppress muscle growth. Myostatin …

Myostatin, a member of the transforming growth factor-β superfamily, is a potent negative
regulator of skeletal muscle growth and is conserved in many species, from rodents to …

Since its identification in 1997, myostatin has been considered as a novel and unique
negative regulator of muscle growth, as mstn−/− mice display a dramatic and widespread …

Background Myostatin is a negative regulator of muscle growth but the relationship between
serum myostatin levels and muscle mass is unclear. This study investigated the association …

Myostatin (also known as growth and differentiation factor 8) is a secreted member of the
transforming growth factor-β (TGF-β) family that is mainly expressed in skeletal muscle …

Myostatin, or GDF-8 (growth and differentiation factor-8), was first identified through
sequence identity with members of the BMP (bone morphogenetic protein)/TGF-β …

Myostatin, a TGF-β family member, is a negative regulator of muscle growth. Here, we
generated transgenic mice that expressed myostatin mutated at its cleavage site under the …

Myostatin, an endogenous negative regulator of skeletal muscle mass, is a therapeutic
target for muscle atrophic disorders. Here, we identified minimum peptides 2 and 7 to …