Accounting for trait architecture in genomic predictions of US Holstein cattle using a weighted realized relationship matrix

F Tiezzi, C Maltecca - Genetics Selection Evolution, 2015 - Springer
Abstract Background Genomic BLUP (GBLUP) can predict breeding values for non-
phenotyped individuals based on the identity-by-state genomic relationship matrix (G). The …

[HTML][HTML] Comparison of genomic predictions for lowly heritable traits using multi-step and single-step genomic best linear unbiased predictor in Holstein cattle

AR Guarini, DAL Lourenco, LF Brito, M Sargolzaei… - Journal of dairy …, 2018 - Elsevier
The success and sustainability of a breeding program incorporating genomic information is
largely dependent on the accuracy of predictions. For low heritability traits, large training …

[HTML][HTML] Comparison of genomic predictions using genomic relationship matrices built with different weighting factors to account for locus-specific variances

G Su, OF Christensen, L Janss, MS Lund - Journal of dairy science, 2014 - Elsevier
Various models have been used for genomic prediction. Bayesian variable selection models
often predict more accurate genomic breeding values than genomic BLUP (GBLUP), but …

Single-step genomic BLUP with many metafounders

AA Kudinov, M Koivula, GP Aamand, I Strandén… - Frontiers in …, 2022 - frontiersin.org
Single-step genomic BLUP (ssGBLUP) model for routine genomic prediction of breeding
values is developed intensively for many dairy cattle populations. Compatibility between the …

Crossbreed evaluations in single-step genomic best linear unbiased predictor using adjusted realized relationship matrices

DAL Lourenco, S Tsuruta, BO Fragomeni… - Journal of animal …, 2016 - academic.oup.com
Combining purebreed and crossbreed information is beneficial for genetic evaluation of
some livestock species. Genetic evaluations can use relationships based on genomic …

Use of biological priors enhances understanding of genetic architecture and genomic prediction of complex traits within and between dairy cattle breeds

L Fang, G Sahana, P Ma, G Su, Y Yu, S Zhang… - BMC genomics, 2017 - Springer
Background A better understanding of the genetic architecture underlying complex traits (eg,
the distribution of causal variants and their effects) may aid in the genomic prediction. Here …

Genomic predictions in purebreds with a multibreed genomic relationship matrix

Y Steyn, DAL Lourenco, I Misztal - Journal of Animal Science, 2019 - academic.oup.com
Combining breeds in a multibreed evaluation can have a negative impact on prediction
accuracy, especially if single nucleotide polymorphism (SNP) effects differ among breeds …

Accuracy of whole-genome prediction using a genetic architecture-enhanced variance-covariance matrix

Z Zhang, M Erbe, J He, U Ober, N Gao… - G3: Genes …, 2015 - academic.oup.com
Obtaining accurate predictions of unobserved genetic or phenotypic values for complex
traits in animal, plant, and human populations is possible through whole-genome prediction …

Genomic prediction using multi-trait weighted GBLUP accounting for heterogeneous variances and covariances across the genome

E Karaman, MS Lund, MT Anche… - G3: Genes, Genomes …, 2018 - academic.oup.com
Implicit assumption of common (co) variance for all loci in multi-trait Genomic Best Linear
Unbiased Prediction (GBLUP) results in a genomic relationship matrix (G) that is common to …

Genomic prediction using alternative strategies of weighted single-step genomic BLUP for yearling weight and carcass traits in Hanwoo beef cattle

H Mehrban, M Naserkheil, DH Lee, C Cho, T Choi… - Genes, 2021 - mdpi.com
The weighted single-step genomic best linear unbiased prediction (GBLUP) method has
been proposed to exploit information from genotyped and non-genotyped relatives, allowing …