Most eukaryotic cells are capable of taking up long-chain fatty acids (LCFAs) to be used for a
variety of cellular processes. Low levels of cellular uptake may occur by simple diffusion of …

Long chain fatty acids (LCFAs) are an important energy substrate used by cardiac myocytes
and other cells, but the mechanism whereby these molecules cross the plasma membrane is …

Fatty acids are a major source of energy for cardiac myocytes. Changes in fatty acid
metabolism have been implicated as causal in diabetes and cardiac disease. The …

Long chain fatty acids (LCFAs) provide 70-80% of the energy for cardiac contractile activity.
LCFAs are also essential for many other cellular functions, such as transcriptional regulation …

Uptake of long chain fatty acids (LCFAs) is a critical function of eukaryotic cells. In the past, a
diffusional mechanism has been proposed for passage of these hydrophobic molecules …

Long-chain fatty acids (LCFAs) are an important energy source for many tissues. The dogma
that LCFAs are freely diffusible has been challenged. It is now known that LCFAs are …

Long chain fatty acids (LCFAs) are an important source of energy for most organisms. They
also function as blood hormones, regulating key metabolic functions such as hepatic …

Despite decades of extensive research, the transport routes, mechanisms of uptake and
points of flux control of long-chain fatty acids (FA) in mammalian organs are still incompletely …

Cardiac uptake of long-chain fatty acids (FA) is mediated predominantly by two membrane-
associated proteins, the 43-kDa plasma membrane fatty acid-binding protein (FABPpm) and …

Protein-mediated LCFA transport across plasma membranes is highly regulated by the fatty
acid transporters FAT/CD36 and FABPpm. Physiologic stimuli (insulin stimulation, AMP …