Background The IL4-590 gene polymorphism has been shown to be associated with
elevated levels of anti-Plasmodium falciparum IgG antibodies and parasite intensity in the …

In this study, we compared the genotype and allele frequencies of the IL-10-1087 A/G and IL-
4-590 C/T single nucleotide polymorphisms in asymptomatic subjects of two sympatric …

This study aimed to examine the effect of IL-4-590 T/C polymorphism on the levels of malaria-
specific IgE, IgG, IgG (1–4) subclasses as well as total IgE in the Fulani and their sympatric …

Functional IL4-590 C/T polymorphisms and the relative amounts of IL4 and IFN-γ were
investigated in relation to severity of malaria in 110 and 169 Thai patients with complicated …

Previous studies identified an allelic variant of the IL4 promoter region (IL4-589T) that
appears to enhance the transcriptional activity of IL4, and is associated with increased IgE …

Polymorphic variability in immune response genes, such as IL12B, encoding the IL-12p40
subunit is associated with susceptibility to severe malaria in African populations. Since the …

Using segregation analyses, control of malaria parasites has previously been linked to a
major gene within the chromosomal region 5q31–33, but also to complex genetic factors in …

Background and Objectives. Malaria infection, caused by Plasmodium falciparum, is the
most lethal and frequently culminates in severe clinical complications. Interleukin‐22 (IL‐22) …

Abstract Objective Interleukin‐10 (IL‐10) is an anti‐inflammatory cytokine produced by Th1
cells and macrophages. The rationale of this study was to examine and validate possible …

The Fulani are less clinically susceptible and more immunologically responsive to malaria
than neighbouring ethnic groups. Here we report that anti-malarial antibody levels show a …