Biofilm formation is an important virulence factor that allows bacteria to resist host responses
and antibacterial agents. The aim of the study was to assess the in vitro activities of several …

Objectives The aim of the study was to assess the in vitro activity of linezolid and
daptomycin, alone and in combination, against three Staphylococcus aureus isolates using …

Introduction Medical device infections are associated with significant morbidity and mortality.
These difficult-to-treat infections often result in antibiotic failure and resistance. Combination …

Biofilm-related infections remain a scourge. In an in vitro model of biofilms using
Staphylococcus aureus reference strains, delafloxacin and daptomycin were found to be the …

The efficacy of commonly used antistaphylococcal antimicrobials (clindamycin, linezolid and
vancomycin) and recently developed antibiotics (daptomycin and tigecycline) was compared …

Biofilms are associated with persistence of Staphylococcus aureus infections and
therapeutic failures. Our aim was to set up a pharmacodynamic model comparing antibiotic …

Due to high resistance, standard chemotherapy of biofilm-associated staphylococcal
infections is ineffective and a number of alternative approaches to antimicrobial treatment …

Objectives To evaluate putative anti-staphylococcal biofilm antibiotic combinations used in
the management of periprosthetic joint infections (PJIs). Methods Using the dissolvable …

The aim of this study was to assess whether the novel lipopeptide daptomycin might be
capable of disrupting or inhibiting the synthesis of biofilms produced by staphylococci …

Staphylococcal biofilms on surgical implants are the underlying cause of a lack of response
to antimicrobial treatment. We investigated the effects of vancomycin (VAN), daptomycin …