Background: Septic acute kidney injury (AKI) causes high mortality in critical care units, and
no effective therapy exists in clinical treatment. In the current study, water and ethanol …

There is increasing evidence to suggest that toxic oxygen radicals play a role in the
pathogenesis of ischemia/reperfusion (I/R) injury in the kidney. This study was designed to …

The neuroprotective effect and mechanism of the flavonoid-rich extract (FRE) from Rosa
laevigata Michx fruit on cerebral ischemia–reperfusion (I/R) injury were investigated. The …

This work aims to evaluate the renoprotective effect of luteolin on expression of Nrf2 and
miR320 in ischemia–reperfusion (I/R) injury in rats. Thirty rats were randomly divided into …

Objective: The present study aims to provide evidence on the potential protective role of
Salvia miltiorrhiza Bunge (Danshen) and its bioactive compound Tanshinone IIA (TanIIA) in …

Honokiol is the predominant active ingredient in the commonly used traditional Chinese
medicine, Magnolia, which has been confirmed in previous studies to exhibit anti‑oxidation …

As a conventional complication of sepsis, acute kidney injury (AKI) is characterized by high
incidence and mortality. Effective management methods are still lacking. Quercetin belongs …

There is increasing evidence to suggest that reactive oxygen metabolites (ROMs) play a role
in the pathogenesis of ischemia/reperfusion injury (I/R) in the kidney. This study was …

Background/Aims: To explore the protective effect of curcumin on renal ischemia-reperfusion
injury (RIRI) in rats, and its influence on nephridial tissue's NO and cGMP levels as well as …

Background: Ischemia-reperfusion injury (IRI) is one of the major causes of postoperative
renal allograft dysfunction, which is mainly the result of proinflammatory reactions including …