Fibrosis, a common pathogenic pathway of chronic liver disease (CLD), has long been
indicated to be significantly and most importantly associated with severe prognosis …

Hepatic fibrogenesis may gradually result to cirrhosis due to the accumulation of
extracellular matrix components as a response to liver injury. Thus, therapeutic decisions in …

The management of patients with chronic liver disease (CLD) requires an accurate definition
of the stag‑ing and grading, as the latter is related to the progression of liver fibrosis. Albeit …

Liver fibrosis is a wound-healing response to a wide spectrum of chronic liver injuries. It is
characterized by loss of hepatocytes and alteration in hepatic architecture following an …

Chronic hepatitis B and C together with alcoholic and non-alcoholic fatty liver diseases
represent the major causes of progressive liver disease that can eventually evolve into …

Chronic liver diseases are very common worldwide, particularly those linked to viral hepatitis
and to alcoholic and non-alcoholic fatty liver. Their natural history is variable and long-term …

Chronic liver diseases represent a major public health problem, accounting for significant
morbidity and mortality worldwide. Their prognosis and management greatly depend on the …

With increasing innovations aimed at the treatment of chronic liver disease (CLD), the
precise staging of liver fibrosis is important to help establish efficacious management of …

Chronic liver disease represents a major public health problem, accounting for significant
morbidity and mortality worldwide. Their prognosis and management greatly depends on the …

Liver fibrosis, that is, excessive accumulation of extracellular matrix protein, occurs and is
the wound-healing response and common final pathway of various chronic liver diseases …