[HTML][HTML] Platelet‐inspired nanomedicine in hemostasis thrombosis and thromboinflammation
Platelets are anucleate cell‐fragments derived predominantly from megakaryocytes in the
bone marrow and released in the blood circulation, with a normal count of 150 000–40 000 …
bone marrow and released in the blood circulation, with a normal count of 150 000–40 000 …
Engineered platelets: advocates for tumor immunotherapy
Platelets are crucial components in the blood circulation mainly responsible for hemostasis,
and they are also widely involved in dynamic physiological activities including inflammation …
and they are also widely involved in dynamic physiological activities including inflammation …
Platelets and their biomimetics for regenerative medicine and cancer therapies
Platelets, circulating blood cells derived from megakaryocytes, play a key role in various
physical activities, including coagulation, hemostasis, the body's innate immune response …
physical activities, including coagulation, hemostasis, the body's innate immune response …
Platelet-mimicking procoagulant nanoparticles augment hemostasis in animal models of bleeding
Treatment of bleeding disorders using transfusion of donor-derived platelets faces logistical
challenges due to their limited availability, high risk of contamination, and short (5 to 7 days) …
challenges due to their limited availability, high risk of contamination, and short (5 to 7 days) …
Platelet-derived drug delivery systems: pioneering treatment for cancer, cardiovascular diseases, infectious diseases, and beyond
Platelets play a critical role as circulating cells in the human body and contribute to essential
physiological processes such as blood clotting, hemostasis, vascular repair, and thrombus …
physiological processes such as blood clotting, hemostasis, vascular repair, and thrombus …
Nanotechnology and primary hemostasis: Differential effects of nanoparticles on platelet responses
Despite the numerous advantages offered by diverse platforms based on nanomedicine,
several nanomaterials have shown significant cell toxicity that could induce chronic adverse …
several nanomaterials have shown significant cell toxicity that could induce chronic adverse …
Recent trends in platelet membrane-cloaked nanoparticles for application of inflammatory diseases
Z Fang, J Fang, C Gao, R Gao, P Lin, W Yu - Drug Delivery, 2022 - Taylor & Francis
Platelets are multifunctional effectors of inflammatory responses and inseparable from the
occurrence and development of various inflammatory diseases. The platelet membrane …
occurrence and development of various inflammatory diseases. The platelet membrane …
Platelet-like nanoparticles: mimicking shape, flexibility, and surface biology of platelets to target vascular injuries
AC Anselmo, CL Modery-Pawlowski, S Menegatti… - ACS …, 2014 - ACS Publications
Targeted delivery of therapeutic and imaging agents in the vascular compartment represents
a significant hurdle in using nanomedicine for treating hemorrhage, thrombosis, and …
a significant hurdle in using nanomedicine for treating hemorrhage, thrombosis, and …
[HTML][HTML] Biomimetic platelet membrane-coated nanoparticles for targeted therapy
H Han, R Bartolo, J Li, MA Shahbazi… - European Journal of …, 2022 - Elsevier
The development of cell membrane-modified biomimetic nanoparticles has extensively
increased during the past years due to their exceptional biocompatibility, evasion from the …
increased during the past years due to their exceptional biocompatibility, evasion from the …
Engineering platelet-mimicking drug delivery vehicles
Platelets dynamically participate in various physiological processes, including wound repair,
bacterial clearance, immune response, and tumor metastasis. Recreating the specific …
bacterial clearance, immune response, and tumor metastasis. Recreating the specific …