Preparation, cellular transport, and activity of polyamidoamine-based dendritic nanodevices with a high drug payload

P Kolhe, J Khandare, O Pillai, S Kannan, M Lieh-Lai… - Biomaterials, 2006 - Elsevier
Dendrimers are emerging as a relatively new class of polymeric biomaterials with
applications in drug delivery, and imaging. Achieving a high drug payload in dendrimers …

Synthesis, cellular transport, and activity of polyamidoamine dendrimer− methylprednisolone conjugates

J Khandare, P Kolhe, O Pillai, S Kannan… - Bioconjugate …, 2005 - ACS Publications
Dendrimers have emerged as promising multifunctional nanomaterials for drug delivery due
to their well-defined size and tailorability. We compare two schemes to obtain …

Recent progress in dendrimer-based nanomedicine development

Y Kim, EJ Park, DH Na - Archives of pharmacal research, 2018 - Springer
Dendrimers offer well-defined nanoarchitectures with spherical shape, high degree of
molecular uniformity, and multiple surface functionalities. Such unique structural properties …

[HTML][HTML] Application of dendrimers in anticancer diagnostics and therapy

Z Bober, D Bartusik-Aebisher, D Aebisher - Molecules, 2022 - mdpi.com
The application of dendrimeric constructs in medical diagnostics and therapeutics is
increasing. Dendrimers have attracted attention due to their compact, spherical three …

Dendrimer‐based nanocarriers: a versatile platform for drug delivery

HJ Hsu, J Bugno, S Lee, S Hong - … Reviews: Nanomedicine and …, 2017 - Wiley Online Library
Advances in nanotechnology have had profound impacts on therapeutic delivery, leading to
the development of nanomaterials engineered with large carrying capabilities and targeting …

A quantitative assessment of nanoparticle− ligand distributions: implications for targeted drug and imaging delivery in dendrimer conjugates

DG Mullen, M Fang, A Desai, JR Baker Jr, BG Orr… - Acs Nano, 2010 - ACS Publications
Functional nanoparticles often contain ligands including targeting molecules, fluorophores,
and/or active moieties such as drugs. Characterizing the number of these ligands bound to …

Poly (amidoamine) dendrimer-erythromycin conjugates for drug delivery to macrophages involved in periprosthetic inflammation

A Bosnjakovic, MK Mishra, W Ren, YE Kurtoglu… - … , Biology and Medicine, 2011 - Elsevier
Erythromycin (EM), an antibiotic that has been used for infectious diseases, is now gaining
attention because of its novel anti-inflammatory effects. We explore a dendrimer-EM …

[HTML][HTML] Dendrimers for drug delivery

AS Chauhan - Molecules, 2018 - mdpi.com
Dendrimers have come a long way in the last 25 years since their inception. Originally
created as a wonder molecule of chemistry, dendrimer is now in the fourth class of polymers …

Poly (amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy

IJ Majoros, TP Thomas, CB Mehta… - Journal of medicinal …, 2005 - ACS Publications
Multifunctional cancer therapeutic nanodevices have been designed and synthesized using
the poly (amidoamine)(PAMAM) dendrimer as a carrier. Partial acetylation of the generation …

Multifunctional dendritic polymers in nanomedicine: opportunities and challenges

J Khandare, M Calderón, NM Dagia… - Chemical Society …, 2012 - pubs.rsc.org
Nanotechnology has resulted in materials that have greatly improved the effectiveness of
drug delivery because of their ability to control matter on the nanoscale. Advanced forms of …