Abstract IgA knockout mice (IgA−/−) were generated by gene targeting and were used to
determine the role of IgA in protection against mucosal infection by influenza and the value …

Objectives Hemagglutination inhibiting (HI) antibodies correlate with influenza vaccine
protection but their association with protection induced by natural infection has received less …

The adaptive immune response to influenza virus infection is multifaceted and complex,
involving antibody and cellular responses at both systemic and mucosal levels. Immune …

Influenza vaccines remain the primary public health tool in reducing the ever-present burden
of influenza and its complications. In seeking more immunogenic, more effective and more …

Background Antibodies directed against haemagglutinin, measured by the
haemagglutination inhibition (HI) assay are essential to protective immunity against …

Vaccination represents the most effective form of protection against influenza infection.
While neutralizing antibodies are typically measured as a correlate of vaccine-induced …

The current pandemic has brought a renewed appreciation for the critical importance of
vaccines for the promotion of both individual and public health. Influenza vaccines have …

Influenza virus causes an acute respiratory infection in humans. Frequent point mutations in
the influenza genome and occasional exchange of genetic segments between virus strains …

Antibody titers are commonly used as surrogate markers for serological protection against
influenza and other pathogens. Detailed knowledge of antibody production pre-and post …

Background. Laboratory correlates of influenza vaccine protection can best be identified by
examining people who are infected despite vaccination. While the importance of antibody to …