Comparisons of the humoral and cellular immune responses induced by live attenuated influenza vaccine and inactivated influenza vaccine in adults

DF Hoft, KR Lottenbach, A Blazevic… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
Both live attenuated influenza vaccines (LAIV) and inactivated influenza vaccines (IIV)
induce protective immunity against influenza. There is evidence that LAIV induces superior …

Vaccination with adjuvanted recombinant neuraminidase induces broad heterologous, but not heterosubtypic, cross-protection against influenza virus infection in mice

TJ Wohlbold, R Nachbagauer, H Xu, GS Tan, A Hirsh… - MBio, 2015 - Am Soc Microbiol
In an attempt to assess the cross-protective potential of the influenza virus neuraminidase
(NA) as a vaccine antigen, different subtypes of recombinant NA were expressed in a …

T-cell immunity to influenza A viruses

EJ Grant, L Chen, S Quinones-Parra… - Critical Reviews™ in …, 2014 - dl.begellhouse.com
Influenza infection remains a global threat to human health. Influenza viruses are normally
controlled by antibodies specific for the surface glycoproteins hemagglutinin (HA) and …

Correlates of vaccine protection from influenza and its complications

JA McCullers, VC Huber - Human vaccines & immunotherapeutics, 2012 - Taylor & Francis
Despite use of influenza vaccines for more than 65 y, influenza and its complications are a
major cause of morbidity and mortality worldwide. Most deaths during influenza virus …

Pregnancy does not attenuate the antibody or plasmablast response to inactivated influenza vaccine

AW Kay, NL Bayless, J Fukuyama, N Aziz… - The Journal of …, 2015 - academic.oup.com
Background. Inactivated influenza vaccine (IIV) is recommended during pregnancy to
prevent influenza infection and its complications in pregnant women and their infants …

Association between antibody titers and protection against influenza virus infection within households

TK Tsang, S Cauchemez, RAPM Perera… - The Journal of …, 2014 - academic.oup.com
Background. Previous studies have established that antibody titer measured by the
hemagglutination-inhibiting (HAI) assay is correlated with protection against influenza virus …

Evaluation of preexisting anti-hemagglutinin stalk antibody as a correlate of protection in a healthy volunteer challenge with influenza A/H1N1pdm virus

JK Park, A Han, L Czajkowski, S Reed, R Athota… - MBio, 2018 - Am Soc Microbiol
Influenza virus hemagglutinin (HA) surface glycoprotein is currently the primary target of
licensed influenza vaccines. Recently, broadly reactive antibodies that target the stalk region …

Measuring influenza neutralizing antibody responses to A (H3N2) viruses in human sera by microneutralization assays using MDCK-SIAT1 cells

FL Gross, Y Bai, S Jefferson, C Holiday… - JoVE (Journal of …, 2017 - jove.com
Neutralizing antibodies against hemagglutinin (HA) of influenza viruses are considered the
main immune mechanism that correlates with protection for influenza infections …

IgM, IgG, and IgA antibody responses to influenza A (H1N1) pdm09 hemagglutinin in infected persons during the first wave of the 2009 pandemic in the United States

ZN Li, SC Lin, PJ Carney, J Li, F Liu, X Lu… - Clinical and Vaccine …, 2014 - Am Soc Microbiol
The novel influenza A (H1N1) pdm09 virus caused an influenza pandemic in 2009. IgM, IgG,
and IgA antibody responses to A (H1N1) pdm09 hemagglutinin (HA) following A (H1N1) …

Assessing the protective potential of H1N1 influenza virus hemagglutinin head and stalk antibodies in humans

SR Christensen, SA Toulmin, T Griesman… - Journal of …, 2019 - Am Soc Microbiol
Seasonal influenza viruses are a major cause of human disease worldwide. Most
neutralizing antibodies (Abs) elicited by influenza viruses target the head domain of the …