Ceftibuten, compared to cefixime, cefetamet, cefpodoxime, loracarbef, cefprozil, cefuroxime,
cefaclor, and cefadroxil, was the most active oral cephalosporin derivative against …

The ability of broad-spectrum β-lactamases to reduce the susceptibility to ceftazidime-
avibactam (CZA), ceftolozane-tazobactam (C/T), imipenem-relebactam, meropenem …

ABSTRACT Extended-spectrum-β-lactamase (ESBL)-producing strains are increasing
worldwide, limiting therapeutic options. Taniborbactam (VNRX-5133) is a newly developed …

Examination of the activity of cefoperazone against ampicillin-resistant, gramnegative
bacteria in agar dilution and simultaneously in broth dilution revealed that strains could be …

Several cephalosporins are in clinical development as broad-spectrum agents with potent
activity against multi-resistant staphylococci as well as the Gram-positive and Gram-negative …

Treatment of infections with carbapenem-resistant Gram negative organism is a major
challenge especially among intensive care patients. Combinations of sulbactam …

The in vitro activity of the new parenteral cephalosporin BMY-28142 was compared with that
of cephalothin, cefoxitin, cefotaxime, ceftriaxone, moxalactam, aztreonam and ceftazidime …

We examined the drug susceptibility pattern of Gram-negative bacilli to seven new beta-
lactams. A total of 277 non-duplicate gramnegative bacilli strains belonging to the …

Objectives: Diazabicyclooctanes (DBOs) inhibit class A, class C and some class D β-
lactamases. A few also bind PBP2, conferring direct antibacterial activity and a β-lactamase …

This study compared the activity of cefepime+ zidebactam (FEP-ZID) and selected currently
available antibacterial agents against a panel of multidrug-resistant (MDR) clinical isolates …