Phosphoinositide 3-kinase regulates membrane Type 1-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry
AR Hess, EA Seftor, REB Seftor, MJC Hendrix - Cancer research, 2003 - AACR
Vasculogenic mimicry (VM) describes the unique ability of highly aggressive melanoma
tumor cells to express endothelial cell-associated genes (such as EphA2 and VE-cadherin) …
tumor cells to express endothelial cell-associated genes (such as EphA2 and VE-cadherin) …
Vasculogenic mimicry: current status and future prospects
S Zhang, D Zhang, B Sun - Cancer letters, 2007 - Elsevier
In 1999, Maniotis reported that blood vessels of highly aggressive uveal melanomas are
formed by tumor cells instead of endothelial cells. He termed this novel concept in tumor …
formed by tumor cells instead of endothelial cells. He termed this novel concept in tumor …
VEGFR1 and PKCα signaling control melanoma vasculogenic mimicry in a VEGFR2 kinase-independent manner
A Vartanian, E Stepanova, I Grigorieva… - Melanoma …, 2011 - journals.lww.com
We have recently shown that vascular endothelial growth factor-A (VEGFA), a major
regulator of tumor vascularization, is essential for the organization of tumor cells into …
regulator of tumor vascularization, is essential for the organization of tumor cells into …
Differential role of tissue factor pathway inhibitors 1 and 2 in melanoma vasculogenic mimicry
W Ruf, EA Seftor, RJ Petrovan, RM Weiss, LM Gruman… - Cancer research, 2003 - AACR
Vasculogenic mimicry (VM), the formation of matrix-rich vascular-like networks in three-
dimensional culture corresponding with the expression of vascular cell-associated genes …
dimensional culture corresponding with the expression of vascular cell-associated genes …
VE-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway: implications for vasculogenic mimicry
The formation of matrix-rich, vasculogenic-like networks, termed vasculogenic mimicry (VM),
is a unique process characteristic of highly aggressive melanoma cells found to express …
is a unique process characteristic of highly aggressive melanoma cells found to express …
Advanced research on vasculogenic mimicry in cancer
Vasculogenic mimicry (VM) is a brand‐new tumour vascular paradigm independent of
angiogenesis that describes the specific capacity of aggressive cancer cells to form vessel …
angiogenesis that describes the specific capacity of aggressive cancer cells to form vessel …
Nicotinamide inhibits vasculogenic mimicry, an alternative vascularization pathway observed in highly aggressive melanoma
O Itzhaki, E Greenberg, B Shalmon, A Kubi, AJ Treves… - PloS one, 2013 - journals.plos.org
Vasculogenic mimicry (VM) describes functional vascular channels composed only of tumor
cells and its presence predicts poor prognosis in melanoma patients. Inhibition of this …
cells and its presence predicts poor prognosis in melanoma patients. Inhibition of this …
Overview of advances in vasculogenic mimicry–a potential target for tumor therapy
H Ge, H Luo - Cancer management and research, 2018 - Taylor & Francis
Vasculogenic mimicry (VM) describes the process utilized by highly aggressive cancer cells
to generate vascular-like structures without the presence of endothelial cells. VM has been …
to generate vascular-like structures without the presence of endothelial cells. VM has been …
[HTML][HTML] Tumor cell vasculogenic mimicry: from controversy to therapeutic promise
REB Seftor, AR Hess, EA Seftor, DA Kirschmann… - The American journal of …, 2012 - Elsevier
In 1999, The American Journal of Pathology published an article entitled “Vascular Channel
Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry,” by …
Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry,” by …
Vasculogenic mimicry: become an endothelial cell “but not so much”
M Fernández-Cortés, D Delgado-Bellido… - Frontiers in …, 2019 - frontiersin.org
Blood vessels supply all body tissues with nutrients and oxygen, take away waste products
and allow the arrival of immune cells and other cells (pericytes, smooth muscle cells) that …
and allow the arrival of immune cells and other cells (pericytes, smooth muscle cells) that …