The Xenopus mid-blastula transition (MBT) marks the onset of large-scale zygotic
transcription, as well as an increase in cell cycle length and a loss of synchronous cell …

Following fertilization, vertebrate embryos delay large-scale activation of the zygotic genome
from several hours in fish and amphibians to several days in mammals. Externally …

During early development, animal embryos depend on maternally deposited RNA until
zygotic genes become transcriptionally active. Before this maternal-to-zygotic transition …

The development of animal embryos is initially directed by maternal gene products. Then,
during the maternal-to-zygotic transition (MZT), developmental control is handed to the …

Embryogenesis depends on a highly coordinated cascade of genetically encoded events. In
animals, maternal factors contributed by the egg cytoplasm initially control development …

Early mammalian development is characterized by extensive changes in nuclear functions
that result from epigenetic modifications of the newly formed embryonic genome. While the …

A zygote is the result of fertilization, fusion of a sperm and an oocyte. In organisms with
sexual reproduction it represents the beginning of embryonic development, of which the first …

The fertilized frog egg contains all the materials needed to initiate development of a new
organism, including stored RNAs and proteins deposited during oogenesis, thus the earliest …

In Xenopus laevis zygotic transcription begins at the midblastula transition (MBT). Prior to
this the genome is organized into chromatin that facilitates rapid cycles of DNA replication …

All animal embryos pass through a stage during which developmental control is handed
from maternally provided gene products to those synthesized from the zygotic genome. This …