Critically ill patients often have systemic activation of both inflammation and coagulation.
Increasing evidence points to an extensive cross-talk between these two systems, whereby …

Severe sepsis is almost invariably associated with systemic activation of coagulation. There
is ample evidence that demonstrates a wide-ranging cross-talk between hemostasis and …

Critically ill patients often have systemic activation of both inflammatory systems and
coagulation. Increasing evidence points to an extensive cross-talk between these two …

In the pathogenesis of sepsis, inflammation and coagulation play a pivotal role. Increasing
evidence points to an extensive cross-talk between these two systems, whereby …

In the majority of patients with severe sepsis, systemic activation of coagulation is present.
Increasing evidence points to an extensive cross-talk between coagulation and inflammation …

Coagulation abnormalities, ranging from a simple fall in platelet count to full-blown
disseminated intravascular coagulation, are a common occurrence in critically ill patients …

In the majority of patients with systemic inflammatory conditions, some degree of activation
of coagulation is present. Increasing evidence points to an extensive cross‐talk between …

Coagulation in severe sepsis: A central role for thrombomodu... : Critical Care Medicine
Coagulation in severe sepsis: A central role for thrombomodulin and activated protein C …

The coagulation system evolved as a mechanism to limit the loss of vital elements from the
internal milieu following mechanical injury to the circulatory system. The innate immune …

Sepsis almost invariably leads to hemostatic abnormalities, ranging from insignificant
laboratory changes to severe disseminated intravascular coagulation. There is compelling …