The accumulation of low-density lipoproteins (LDL) in the arterial wall plays a pivotal role in
the initiation and pathogenesis of atherosclerosis. Conversely, the removal of cholesterol …

Transendothelial lipoprotein transport and regulation of end... : Current Opinion in Lipidology
Transendothelial lipoprotein transport and regulation of endothelial permeability and integrity by …

Seminal studies from Nikolai Anichckov identified the accumulation of cholesterol in the
arteries as the initial event that lead to the formation of atherosclerotic plaques. Further …

High density lipoprotein (HDL) cholesterol is an important risk factor for coronary heart
disease, and HDL exerts various potentially antiatherogenic properties, including the …

The vascular endothelium serves as a barrier between the intravascular and extravascular
compartments. High-density lipoproteins (HDL) have two kinds of interactions with this …

High-density lipoproteins (HDLs) are among the most structurally complex and functionally
versatile forms of circulating serum lipoproteins. HDLs undergo extensive enzymatic …

Objective—Low-and high-density lipoproteins (LDL and HDL) must pass the endothelial
layer to exert pro-and antiatherogenic activities, respectively, within the vascular wall …

Summary Caveolae, ALK1 and SR-B1 are identified as key regulators in the LDL
transcytosis across the endothelium. Endothelial LDL transcytosis might be a potential …

Reverse cholesterol transport (RCT) is a pathway by which accumulated cholesterol is
transported from the vessel wall to the liver for excretion, thus preventing atherosclerosis …

Accumulation of atherogenic lipoproteins in the arterial intima is a key event in the
development of atherosclerosis. The likelihood of increased lipoprotein accumulation in the …