Reverse cholesterol transport (RCT) describes the process whereby cholesterol in
peripheral tissues is transported to the liver where it is ultimately excreted in the form of bile …

Accumulation of cholesterol by macrophages, leading to their transformation into foam cells
is a key event in the initiation of atherosclerosis. As maintenance of cholesterol homeostasis …

In this review we shall examine the current understanding of events that lead to the incipient
formation of the early foam cell lesion in atherogenesis and its localization. Particular …

In the past six years the transport of serum lipids via a system of lipoproteins has been
described in detail. 1–7 It is our purpose here to describe the physiology of this lipoprotein …

LDL and other cholesterol-rich, apoB-containing lipoproteins, once they become retained
and modified within the arterial wall, cause atherosclerosis. This simple, robust …

Plasma high density lipoprotein (HDL) levels bear a strong independent inverse relationship
with atherosclerotic cardiovascular disease. Although HDL has anti‐oxidant, anti …

Atherosclerosis is a major contributor to the onset and progression of cardiovascular
disease (CVD). Cholesterol‐loaded foam cells play a pivotal role in forming atherosclerotic …

Human umbilical vein endothelial cell monolayers were grown as monolayers on porous
filters and their transcellular transport and degradation of 125 I-labelled native and modified …

Over the past 10 years, many advances have been made in our understanding of the
intravascular metabolism of triglyceride-rich lipoproteins. It is now known that the complex …

Smooth muscle and endothelial cells in vivo are quiescent yet exposed to high levels of
lipoprotein lipids. Phospholipid (PL) and free cholesterol (FC) efflux maintain homeostasis …