Membrane-targeting approaches for enhanced cancer cell destruction with irreversible electroporation
Irreversible electroporation (IRE) is a promising technology to treat local malignant cancer
using short, high-voltage electric pulses. Unfortunately, in vivo studies show that IRE suffers …
using short, high-voltage electric pulses. Unfortunately, in vivo studies show that IRE suffers …
Pulse timing during irreversible electroporation achieves enhanced destruction in a hindlimb model of cancer
The use of irreversible electroporation (IRE) for cancer treatment has increased during the
past decade due to many advantages over other focal therapies. However, despite early …
past decade due to many advantages over other focal therapies. However, despite early …
Synergistic combinations of short high-voltage pulses and long low-voltage pulses enhance irreversible electroporation efficacy
Abstract Irreversible electroporation (IRE) uses~ 100 μs pulsed electric fields to disrupt cell
membranes for solid tumor ablation. Although IRE has achieved exciting preliminary clinical …
membranes for solid tumor ablation. Although IRE has achieved exciting preliminary clinical …
Mathematical modeling of irreversible electroporation for treatment planning
JF Edd, RV Davalos - Technology in cancer research & …, 2007 - journals.sagepub.com
Irreversible Electroporation (IRE) is a new drug-free method to ablate undesirable tissue of
particular use in cancer therapy. IRE achieves cell death within the targeted tissue through a …
particular use in cancer therapy. IRE achieves cell death within the targeted tissue through a …
Electrode activation sequencing employing conductivity changes in irreversible electroporation tissue ablation
AV Sahakian, HM Al-Angari… - IEEE transactions on …, 2011 - ieeexplore.ieee.org
Irreversible electroporation (IRE) uses high-voltage pulses applied to tissue, which cause
dielectric breakdown of cell membranes resulting in cell death. IRE is a promising technique …
dielectric breakdown of cell membranes resulting in cell death. IRE is a promising technique …
Physical and chemical enhancement of and adaptive resistance to irreversible electroporation of pancreatic cancer
Q Shao, F Liu, C Chung, K Elahi-Gedwillo… - Annals of biomedical …, 2018 - Springer
Irreversible electroporation (IRE) can be used to treat cancer by electrical pulses, with
advantages over traditional thermal approaches. Here we assess for the first time the IRE …
advantages over traditional thermal approaches. Here we assess for the first time the IRE …
A 2-D cell layer study on synergistic combinations of high-voltage and low-voltage irreversible electroporation pulses
Y Lv, C Yao, B Rubinsky - IEEE Transactions on Biomedical …, 2019 - ieeexplore.ieee.org
Irreversible electroporation (IRE) employs brief, high-electric field pulses to ablate tumors
while preserving the extracellular matrix. Recently, we showed that combining short high …
while preserving the extracellular matrix. Recently, we showed that combining short high …
Bursts of bipolar microsecond pulses inhibit tumor growth
Irreversible electroporation (IRE) is an emerging focal therapy which is demonstrating utility
in the treatment of unresectable tumors where thermal ablation techniques are …
in the treatment of unresectable tumors where thermal ablation techniques are …
Chemical enhancement of irreversible electroporation: A review and future suggestions
Irreversible electroporation has raised great interest in the past decade as a means of
destroying cancers in a way that does not involve heat. Irreversible electroporation is a novel …
destroying cancers in a way that does not involve heat. Irreversible electroporation is a novel …
Tissue heterogeneity in structure and conductivity contribute to cell survival during irreversible electroporation ablation by “electric field sinks”
Irreversible electroporation (IRE) is an emerging, minimally invasive technique for solid
tumors ablation, under clinical investigation for cancer therapy. IRE affects only the cell …
tumors ablation, under clinical investigation for cancer therapy. IRE affects only the cell …
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