Eight-hour continuous normothermic ex vivo kidney perfusion is a safe preservation technique for kidney transplantation: a new opportunity for the storage …

JM Kaths, J Echeverri, N Goldaracena, KS Louis… - …, 2016 - journals.lww.com
Background Hypothermic kidney storage causes preservation injury and is poorly tolerated
by renal grafts. We investigated whether static cold storage (SCS) can be safely replaced …

[HTML][HTML] Continuous normothermic ex vivo kidney perfusion is superior to brief normothermic perfusion following static cold storage in donation after circulatory death …

JM Kaths, JY Cen, YM Chun, J Echeverri… - American Journal of …, 2017 - Elsevier
Hypothermic preservation is known to cause renal graft injury, especially in donation after
circulatory death (DCD) kidney transplantation. We investigated the impact of cold storage …

Normothermic ex vivo kidney perfusion for human kidney transplantation: first North American results

LI Mazilescu, P Urbanellis, SJ Kim, T Goto… - …, 2022 - journals.lww.com
Background. Normothermic ex vivo kidney perfusion (NEVKP) has shown promising results
for preservation, assessment, and reconditioning of kidney allografts in preclinical studies …

Normothermic Ex Vivo Kidney Perfusion Following Static Cold Storage—Brief, Intermediate, or Prolonged Perfusion for Optimal Renal Graft Reconditioning?

JM Kaths, J Echeverri, I Linares, JY Cen… - American Journal of …, 2017 - Wiley Online Library
Normothermic ex vivo kidney perfusion (NEVKP) demonstrated superior results compared to
hypothermic storage in donation after circulatory death (DCD) kidney transplantation. It is …

[HTML][HTML] Normothermic ex vivo kidney perfusion for graft quality assessment prior to transplantation

JM Kaths, M Hamar, J Echeverri, I Linares… - American Journal of …, 2018 - Elsevier
Normothermic ex vivo kidney perfusion (NEVKP) represents a novel approach for graft
preservation and functional improvement in kidney transplantation. We investigated whether …

Normothermic ex vivo kidney perfusion for the preservation of kidney grafts prior to transplantation

JM Kaths, VN Spetzler, N Goldaracena… - JoVE (Journal of …, 2015 - jove.com
Kidney transplantation has become a well-established treatment option for patients with end-
stage renal failure. The persisting organ shortage remains a serious problem. Therefore, the …

Normothermic ex vivo kidney perfusion improves early DCD graft function compared with hypothermic machine perfusion and static cold storage

P Urbanellis, M Hamar, JM Kaths, D Kollmann… - …, 2020 - journals.lww.com
Background. Better preservation strategies for the storage of donation after circulatory death
grafts are essential to improve graft function and to increase the kidney donor pool. We …

Normothermic ex vivo kidney perfusion reduces warm ischemic injury of porcine kidney grafts retrieved after circulatory death

M Hamar, P Urbanellis, MJ Kaths, D Kollmann… - …, 2018 - journals.lww.com
Background Cold storage is poorly tolerated by kidney grafts retrieved after donation after
circulatory death. It has been determined that normothermic ex vivo kidney perfusion …

A pilot study assessing the feasibility of a short period of normothermic preservation in an experimental model of non heart beating donor kidneys

SA Hosgood, AD Barlow, PJ Yates, MGJ Snoeijs… - Journal of Surgical …, 2011 - Elsevier
BACKGROUND: Restoring metabolism to an organ after hypothermic storage and before
transplantation could reverse some of the detrimental effects of ischemic injury. This may be …

Continuous normothermic ex vivo kidney perfusion improves graft function in donation after circulatory death pig kidney transplantation

JM Kaths, J Echeverri, YM Chun, JY Cen… - …, 2017 - journals.lww.com
Background Donation after circulatory death (DCD) is current clinical practice to increase the
donor pool. Deleterious effects on renal graft function are described for hypothermic …