Fluorometric determination of norgestrel and structurally related steroids

LF Cullen, JG Rutgers, PA Lucchesi… - Journal of Pharmaceutical …, 1968 - Elsevier
A sensitive procedure, based on sulfuric acid-induced fluorescence, has been developed for
the analysis of norgestrel (dl-13-ethyl-17α-ethinyl-17-hydroxygon-4-en-3-one) in tablets of …

Automated colorimetric assay of Norgestrel

PM Short, CT Rhodes - Steroids, 1970 - Elsevier
A relatively sensitive assay for the contraceptive steroid norgestrel, in pharmaceutical
preparations, is described. The procedure involves the blue tetrazolium reaction. Optimum …

Norgestrel

AM Sopirak, LF Cullen - Analytical Profiles of Drug Substances, 1975 - Elsevier
Publisher Summary This chapter discusses the norgestrel. Norgestrel is designated as d1-
13-ethyl-l7-ethynyl–17–hydroxygen–4–en-3–one and is listed in the subject indices of …

[引用][C] Metabolites of norgestrel (Wyeth 3707) in humans

P Littleton, K Fortherby - European Journal of Endocrinology, 1967 - academic.oup.com
the most potent progestational steroids; it is a totally synthetic compound and the prepa-
ration normally used is a mixture of the LandD forms, although only the latter is biologic-ally …

Spectrophotofluorometric determination of methyltestosterone in plasma or serum

D Alkalay, L Khemani, MF Bartlett - Journal of Pharmaceutical Sciences, 1972 - Elsevier
For determination of the relative bioavailability of methyltestosterone in man, a
spectrophotofluorometric procedure was developed, based on fluorescence induced by …

Fluoxymesterone analysis by gas chromatography

MW Ruchelman - Clinica Chimica Acta, 1969 - Elsevier
A new method for analyzing fluoxymesterone by gas chromatography utilizes the large
difference in polarity between it and other ketosteroids. Its retention time is selectively shifted …

The identification of some human metabolites of norgestrel, a new progestational agent

DC DeJongh, JD Hribar, P Littleton, K Fotherby… - Steroids, 1968 - Elsevier
Administration of norgestrel I (racemic 13β-ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one)
to humans has been shown by mass spectrometry and other analytical techniques to yield a …

High-performance liquid chromatography and gas-liquid chromatography of some norgestrel intermediates: Physical properties of the isolated syn-and anti-isomers of …

M Patthy, É Tomori - Journal of Chromatography A, 1980 - Elsevier
High-performance liquid chromatographic (HPLC) and gas-liquid chromatographic (GLC)
separations of some steroidal α, β-unsaturated ketoximes, intermediates in the synthesis of …

Determination of 17α-Ethynylestradiol-3-Methyl Ether in Tablets by a Colorimetric Assay

AP Shroff, RE Huettemann - Journal of Pharmaceutical Sciences, 1967 - Elsevier
A colorimetric method has been developed for assaying 17α-ethynylestradiol-3-methyl ether
in tablets. The method is based on the formation of a colored complex with phenol–sulfuric …

Quantitative estimation of components of combined hormonal contraceptives by HPLC

TA Denisova, VV Chistyakov… - Pharmaceutical Chemistry …, 2008 - Springer
Published methods for the quantitative estimation (colorimetry, UV spectrophotometry, and
fluorimetry) of the active components of oral contraceptives do not meet specificity …