As an important energy reservoir, adipose tissue maintains lipid balance and regulates
energy metabolism. When the body requires energy, adipocytes provide fatty acids to …

Obesity-induced insulin resistance is a major risk factor for the development of type 2
diabetes. Basal fat cell lipolysis (ie, fat cell triacylglycerol breakdown into fatty acids and …

Adipose Tissue Lipolysis Revisited (Again!): Lactate Involvement in Insulin Antilipolytic Action
Page 1 Cell Metabolism Previews Adipose Tissue Lipolysis Revisited (Again!): Lactate …

Obesity is defined as excessive accumulation of body fat in proportion to body size. When
obesity occurs, the functions of adipose tissue may be deregulated, which is termed as …

Adipose tissue lipolysis is the catabolic process leading to the breakdown of triglycerides
stored in fat cells and the release of fatty acids and glycerol. Recent work has revealed that …

Human obesity and its complications are an increasing burden in developed and
underdeveloped countries. Adipose tissue mass and the mechanisms that control it are …

Triglycerides in adipose tissue are rapidly mobilized during times of energy needs via
lipolysis, a catabolic process that plays important role in whole body triglyceride turnover …

Aims/hypothesis Impaired regulation of lipolysis and accumulation of lipid intermediates may
contribute to obesity-related insulin resistance and type 2 diabetes mellitus. We investigated …

Adaptation to changes in energy availability is pivotal for the survival of animals. Adipose
tissue, the body's largest reservoir of energy and a major source of metabolic fuel, exerts a …

The aim of this review is to summarize the mechanisms underlying insulin resistance in
morbid obesity. Glucose regulation by insulin depends on the suppression of endogenous …