Background A form of cancer that affects the rectum or colon (large intestine) is called
colorectal cancer (CRC). The main risk factors for CRC include dietary, lifestyle, and …

Chemotherapy resistance is still a serious problem in the treatment of most cancers. Many
cellular and molecular mechanisms contribute to both inherent and acquired drug …

Background: Colorectal Cancer (CRC) ranks third among all cancer-related deaths around
the globe. Chemotherapy may prolong the survival of CRC patients to some extent, but its …

Colorectal cancer (CRC) is one of the most prevalent cancers that threaten people in many
countries. It is a multi-factorial chronic disease caused by a combination of genetic and …

Resistance to chemotherapy remains a major impediment to the management of most types
of cancer. Both intrinsic and acquired drug resistance are mediated by several cellular and …

Acquired drug resistance represents a major clinical problem and one of the biggest
limitations of chemotherapeutic regimens in colorectal cancer. Combination regimens using …

Plant-derived compounds, specifically antioxidants, have played an important role in
scavenging the free radicals present under diseased conditions. The persistent generation …

In today's scenario, when cancer cases are increasing rapidly, anticancer herbal
compounds become imperative. Studies on the molecular mechanisms of action of …

Polyphenolic compounds, encompassing flavonoids (eg, quercetin, rutin, and cyanidin) and
non-flavonoids (eg, gallic acid, resveratrol, and curcumin), show several health-related …

Colorectal cancer (CRC) is a major cause of cancer-related deaths worldwide, underscoring
the importance of understanding the diverse molecular and genetic underpinnings of CRC …