Polyphenols, also known as phenolic compounds, are chemical substances containing
aromatic rings as well as at least two hydroxyl groups. Natural phenolic compounds exist …

Colorectal cancer (CRC) therapy using conventional chemotherapeutics represents a
considerable burden for the patient's organism because of high toxicity while the response is …

The intestine is critically crucial for nutrient absorption and host defense against exogenous
stimuli. Inflammation-related intestinal diseases, including enteritis, inflammatory bowel …

Multidrug resistance (MDR) resulting from different defensive mechanisms in cancer is one
of the major obstacles of clinical treatment. To circumvent MDR many reversal agents have …

Polyphenols represent a structural class of mainly natural organic chemicals that contain
multiple phenol structural units. The beneficial properties of polyphenols have been …

Genetic alterations trigger various cell signaling pathways by transforming the cell cycle of a
normal cell into a cancer cell. Flavonoids are abundantly expressed in natural foods which …

Cancer is a diverse class of diseases characterized by uncontrolled cell growth with the
potential to invade and spread to other parts of the body, and continues to be one of the …

Despite significant advancements made in the treatment of cancer during the past several
decades, it remains one of the leading causes of death worldwide killing approximately 9.6 …

The cytoprotective and anticancer action of dietary in-taken natural polyphenols has for long
been attributed only to their direct radical scavenging activities. Currently it is well supported …

Colorectal cancer (CRC) is the third most common type of cancer in the world, causing
thousands of deaths annually. Although chemotherapy is known to be an effective treatment …