The NF-E2-related factor 2 (Nrf2)-mediated signalling pathway provides living organisms an
efficient and pivotal line of defensive to counteract environmental insults and endogenous …

Oxygen is vital for life as it is required for many different enzymatic reactions involved in
intermediate metabolism and xenobiotic biotransformation. Moreover, oxygen consumption …

This study investigated the potential effect of diallyl disulfide (DADS) against carbon
tetrachloride (CCl 4)-induced oxidative hepatic damage and inflammatory response in rat …

It is widely believed that consuming foods and beverages that have high concentrations of
antioxidants can prevent cardiovascular diseases and many types of cancer. As a result …

Living organisms are surrounded with heavy metals such as methylmercury, manganese,
cobalt, cadmium, arsenic, as well as pesticides such as deltamethrin and paraquat, or …

Oxidative stress occurs when cellular reactive oxygen species levels exceed the self-
antioxidant capacity of the body. Oxidative stress induces many pathological changes …

Cells in vivo are constantly exposed to reactive oxygen species (ROS) generated
endogenously and exogenously. To defend against the deleterious consequences of ROS …

Activation of NF‐E2‐related factor 2 (Nrf2) is a potential therapeutic intervention against
endothelial cell oxidative stress and associated vascular disease. We hypothesized that …

Alcoholic liver disease (ALD) remains to be a worldwide health problem. It is generally
accepted that oxidative stress plays critical roles in the pathogenesis of ALD, and antioxidant …

Oleanolic acid is a plant-derived triterpenoid, which protects against various hepatotoxicants
in rodents. In order to determine whether oleanolic acid activates nuclear factor erythroid 2 …