Vascular endothelial growth factor (VEGF) is an angiogenic growth factor that is a primary
stimulant of the vascularization of solid tumors. VEGF production is induced by oncogenic …

Vascular endothelial growth factor (VEGF) is a primary stimulant of the vascularization of
solid tumors and has therefore been the focus of intense research aimed at blocking its …

Vascular endothelial growth factor (VEGF) is a multifunctional angiogenic growth factor that
is a primary stimulant of the development and maintenance of a vascular network in …

Vascular endothelial growth factor (VEGF) is one of the key factors in tumor
neoangiogenesis, acting through its receptors KDR (VEGFR-2) and fit-1 (VEGFR-1) …

We generated a panel of eight rat IgG 2a monoclonal antibodies with high affinity for mouse
VEGFR2 (KDR/Flk-1), the main receptor that mediates the angiogenic effect of VEGF-A. The …

Vascular targeting agents, which selectively destroy tumor blood vessels, are attractive
agents for the treatment of solid tumors. They differ from anti-angiogenic agents in that they …

Vascular endothelial growth factor (VEGF) is a homodimeric glycoprotein with a molecular
weight of approximately 45 kDa. It is the key mediator of angiogenesis (the formation of new …

Considerable evidence is gathering for the involvement of vascular endothelial growth factor
(VEGF) in the vascularization and growth of primary tumours as well as in the formation of …

Background Vascular endothelial growth factor (VEGF) is a specific endothelial cell mitogen
that stimulates angiogenesis and plays a crucial role in tumor growth. The aim of the present …

Purpose: Vascular endothelial growth factor (VEGF) signaling is key to tumor angiogenesis
and is an important target in the development of anticancer drugs. However, VEGF receptor …