Rapidly emerging evidence implicates perineuronal nets (PNNs) and extracellular matrix
(ECM) molecules that compose or interact with PNNs, in the pathophysiology of several …

Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain
neurons in the CNS during development and control plasticity in the adult CNS. They appear …

Perineuronal nets (PNNs) were shown to be markedly altered in subjects with
schizophrenia. In particular, decreases of PNNs have been detected in the amygdala …

Schizophrenia is a complex brain disorder associated with deficits in synaptic connectivity.
The insidious onset of this illness during late adolescence and early adulthood has been …

Synapses are specialized structures that mediate rapid and efficient signal transmission
between neurons and are surrounded by glial cells. Astrocytes develop an intimate …

Perineuronal nets (PNN) are extracellular matrix (ECM) assemblies that preferentially
ensheath parvalbumin (PV) expressing interneurons. Converging evidence indicates that …

All components of the CNS are surrounded by a diffuse extracellular matrix (ECM)
containing chondroitin sulphate proteoglycans (CSPGs), heparan sulphate proteoglycans …

Perineuronal nets (PNNs) in the brain are condensed glycosaminoglycan-rich extracellular
matrix structures with heterogeneous composition yet specific organization. They typically …

Perineuronal nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan
(CSPG)-containing structures that surround the soma and dendrites of various mammalian …

Perineuronal nets (PNNs) are condensed extracellular matrix (ECM) structures found
throughout the central nervous system that regulate plasticity. They consist of a …