Contributions of eosinophils to human health and disease

AD Klion, SJ Ackerman… - Annual Review of …, 2020 - annualreviews.org
The human eosinophil has long been thought to favorably influence innate mucosal
immunity but at times has also been incriminated in disease pathophysiology. Research into …

Eosinophils: multifaceted biological properties and roles in health and disease

H Kita - Immunological reviews, 2011 - Wiley Online Library
Eosinophils are leukocytes resident in mucosal tissues. During T‐helper 2 (Th2)‐type
inflammation, eosinophils are recruited from bone marrow and blood to the sites of immune …

Eosinophils: changing perspectives in health and disease

HF Rosenberg, KD Dyer, PS Foster - Nature Reviews Immunology, 2013 - nature.com
Eosinophils have been traditionally perceived as terminally differentiated cytotoxic effector
cells. Recent studies have profoundly altered this simplistic view of eosinophils and their …

[HTML][HTML] Eosinophils and eosinophilic immune dysfunction in health and disease

DJ Jackson, P Akuthota… - European Respiratory …, 2022 - Eur Respiratory Soc
The functions ascribed to eosinophils have classically been limited to host defence against
certain parasitic infections and potentially deleterious effects in the setting of specific …

Functions of tissue-resident eosinophils

PF Weller, LA Spencer - Nature Reviews Immunology, 2017 - nature.com
Eosinophils are a prominent cell type in particular host responses such as the response to
helminth infection and allergic disease. Their effector functions have been attributed to their …

Changing roles of eosinophils in health and disease

GT Furuta, FD Atkins, NA Lee, JJ Lee - Annals of allergy, asthma & …, 2014 - Elsevier
Objective To review and highlight the unappreciated roles of eosinophils suggested by
recent studies. Data Sources The literature, unpublished observations, and insights by the …

[HTML][HTML] The emerging roles of eosinophils in mucosal homeostasis

K Shah, A Ignacio, KD McCoy, NL Harris - Mucosal immunology, 2020 - Elsevier
Eosinophils are granulocytes, typically implicated as end-stage effector cells in type-II
immune responses. They are capable of producing a wide array of pre-formed molecules …

The eosinophil

ME Rothenberg, SP Hogan - Annu. Rev. Immunol., 2006 - annualreviews.org
Eosinophils have been considered end-stage cells involved in host protection against
parasites. However, numerous lines of evidence have now changed this perspective by …

Advances in the immunobiology of eosinophils and their role in disease

GM Walsh - Critical reviews in clinical laboratory sciences, 1999 - Taylor & Francis
Eosinophils play a protective role in host immunity to infections by parasitic worms and,
detrimentally, are involved in the pathophysiology of asthma and other allergic diseases …

Eosinophils: singularly destructive effector cells or purveyors of immunoregulation?

EA Jacobsen, AG Taranova, NA Lee, JJ Lee - Journal of Allergy and …, 2007 - Elsevier
Eosinophils are granulocytes typically associated with immune responses to a limited
number of specific insults, including helminth infection and exposure to various allergens …