Aims: Parkinson's disease (PD) is a neurodegenerative disorder characterized by loss of
dopaminergic neurons in the substantia nigra (SN) and diminished dopamine levels in the …

Abstract Ginsenoside Rg1 (Rg1) is a major bioactive ingredient in Panax ginseng that has
low toxicity and has been shown to have neuroprotective effects. The objectives of the …

Previous studies have reported that ginsenoside‑Rg1 (G‑Rg1) was able to mitigate the loss
of dopaminergic neurons in animal models of Parkinson's disease (PD). The present study …

Abstract Ginsenoside Rg3, extracted from Panax ginseng CA Meyer, has been shown to
possess neuroprotective properties. The present study aims to investigate the …

Ginsenoside Rb1 has been demonstrated to protect dopaminergic (DA) neurons from death
in vitro. However, the neuroprotective effects and underlying mechanism of Rb1 in treating …

Background and purpose: We have shown that ginsenoside Rg1 is a novel class of potent
phytoestrogen and activates insulin‐like growth factor‐I receptor (IGF‐IR) signalling pathway …

Emerging evidence shows that psychological stress promotes the progression of
Parkinson's disease (PD) and the onset of dyskinesia in non-PD individuals, highlighting a …

To date, no drug has been proven to be neuroprotective or disease‐modifying for
Parkinson's disease (PD) in clinical trials. Here, we aimed to assess preclinical evidence of …

Huntington's disease (HD) is one of main neurodegenerative diseases, characterized by
striatal atrophy, involuntary movements, and motor incoordination. Ginsenoside Rg1 (Rg1) …

Parkinson's disease is a chronic, multifactorial and progressive neurologic condition that
affects around six million people worldwide, normally over 60 years of age, and is …