Genetic basis for multimodal relationship between apolipoprotein (a) size and lipoprotein (a) concentration in Mexican-Americans

DL Rainwater - Atherosclerosis, 1995 - Elsevier
The reported general inverse relationship between apolipoprotein (a)(apo (a)) size and
plasma lipoprotein (a)(Lp (a)) concentrations was further characterized using 927 samples …

Characterization of the genetic elements controlling lipoprotein (a) concentrations in Mexican Americans. Evidence for at least three controlling elements linked to LPA …

DL Rainwater, CM Kammerer, JL VandeBerg… - Atherosclerosis, 1997 - Elsevier
Analyses of 1163 samples from the San Antonio Family Heart Study revealed several
elements of genetic control of lipoprotein (a)(Lp (a)) concentrations in Mexican Americans …

Apolipoprotein (a) genetic polymorphism and serum lipoprotein (a) concentration in patients with peripheral vascular disease

J Pedro-Botet, M Senti, T Auguet, X Nogués… - Atherosclerosis, 1993 - Elsevier
Abstract Serum lipoprotein (a)(Lp (a)) levels were measured in 89 men with peripheral
vascular disease (PVD) and 129 (100 male and 29 woman) healthy controls. Apolipoprotein …

[PDF][PDF] The effect of genetic determinants of low density lipoprotein levels on lipoprotein (a)

PN Hopkins, RR Williams - Clin Invest Med, 1991 - researchgate.net
Abstract Levels of Lipoprotein (a)[Lp (a)] correlate directly with atherosclerosis risk. The Lp
(a) particle is physically and chemically similar to low density lipoprotein (LDL), the main …

[PDF][PDF] The Apo (a) gene is the major determinant of variation in plasma Lp (a) levels in African Americans

V Mooser, D Scheer, SM Marcovina, J Wang… - The American Journal of …, 1997 - cell.com
The distributions of plasma lipoprotein (a), or Lp (a), levels differ significantly among ethnic
groups. Individuals of African descent have a two-to threefold higher mean plasma level of …

Apo (a) isoforms predict risk for coronary heart disease. A study in six populations.

C Sandholzer, N Saha, JD Kark, A Rees… - … and thrombosis: a …, 1992 - Am Heart Assoc
Elevated concentrations of lipoprotein (a)(Lp [a]) in plasma are associated with premature
coronary heart disease (CHD). Lp (a) levels are largely determined by alleles at the …

LPA gene: interaction between the apolipoprotein(a) size ('kringle IV' repeat) polymorphism and a pentanucleotide repeat polymorphism influences Lp(a) lipoprotein …

O Røsby, K Berg - Journal of internal medicine, 2000 - Wiley Online Library
Røsby O, Berg K (University of Oslo and Ullevål University Hospital, Oslo, Norway). LPA
gene: interaction between the apolipoprotein (a) size ('kringle IV'repeat) polymorphism and …

Apo (a) Variants and Lipoprotein (a) in Men with or without Myocardial infarction

G Chimienti, BL Lamanuzzi, M Nardulli… - … and molecular pathology, 2002 - Elsevier
The lipoprotein Lp (a) with high plasma concentration is an independent genetic
determinant for cardiovascular diseases. It was investigated as a quantitative factor of risk for …

C/T polymorphism in the 5′ untranslated region of the apolipoprotein (a) gene introduces an upstream ATG and reduces in vitro translation

BR Zysow, GE Lindahl, DP Wade… - … , and vascular biology, 1995 - Am Heart Assoc
Elevated plasma levels of lipoproteinz (a)[Lp (a)] are a significant independent risk factor for
arteriosclerosis. Interindividual levels of Lp (a) vary nearly 1000-fold and are mainly due to …

The relation of lipoprotein [a] concentrations and apolipoprotein [a] phenotypes with asymptomatic atherosclerosis in subjects of the Atherosclerosis Risk in …

SA Brown, JD Morrisett, E Boerwinkle… - … and thrombosis: a …, 1993 - Am Heart Assoc
Plasma levels of lipoprotein [a](Lp [a]) are associated with increased risk of coronary artery
disease and show an inverse correlation with apolipoprotein [a](apo [a]) molecular weight …