Sequence polymorphisms in the apolipoprotein (a) gene. Evidence for dissociation between apolipoprotein (a) size and plasma lipoprotein (a) levels.

JC Cohen, G Chiesa, HH Hobbs - The Journal of clinical …, 1993 - Am Soc Clin Investig
Apolipoprotein (a)[apo (a)], an apolipoprotein unique to lipoprotein (a)[Lp (a)], is highly
polymorphic in size. Previous studies have indicated that the size of the apo (a) gene tends …

Lipoprotein (a) levels, apo (a) isoform size, and coronary heart disease risk in the Framingham Offspring Study

S Lamon-Fava, SM Marcovina, JJ Albers… - Journal of lipid …, 2011 - ASBMB
The aim of this study was to assess the independent contributions of plasma levels of
lipoprotein (a)(Lp (a)), Lp (a) cholesterol, and of apo (a) isoform size to prospective coronary …

Segregation analysis of plasma lipoprotein (a) levels in pedigrees with molecularly defined familial hypercholesterolemia

Y Friedlander, E Leitersdorf - Genetic epidemiology, 1995 - Wiley Online Library
The role of genetic and environmental factors in determining the variability in plasma
lipoprotein (a)[Lp (a)] levels was investigated in 220 members of 14 families with familial …

Genome-and exome-wide association study of serum lipoprotein (a) in the Jackson Heart Study

J Li, LA Lange, J Sabourin, Q Duan, W Valdar… - Journal of human …, 2015 - nature.com
Abstract Lipoprotein (a)(Lp (a)) is an independent risk factor for cardiovascular disease. Lp
(a) levels in African Americans (AAs) are much higher compared with that in European …

Expressed hypervariable polymorphism of apolipoprotein (a).

MI Kamboh, RE Ferrell, BA Kottke - American journal of human …, 1991 - ncbi.nlm.nih.gov
Elevated plasma lipoprotein (a)(LP (a] levels are an independent predictor of the
development of premature atherosclerosis in humans. The LP (a) particle consists of two …

Two common polymorphisms in the APO A‐IV coding gene: Their evolution and linkage disequilibrium

M Ilyas kamboh, RF Hamman, RE Ferrell… - Genetic …, 1992 - Wiley Online Library
Abstract Human apolipoprotein A‐IV (APO A‐IV) exhibits a common protein polymorphism
detectable by isoelectric focusing (IEF) due to a single base substitution at codon 360 which …

Apolipoprotein (a) size and pentanucleotide repeat polymorphisms are associated with the degree of atherosclerosis in coronary heart disease

H Amemiya, T Arinami, S Kikuchi… - Atherosclerosis, 1996 - Elsevier
To evaluate whether a high level of lipoprotein (a)(Lp (a)) is a risk for the development of
coronary heart disease (CHD), 94 Japanese patients and 64 age-matched Japanese …

Comparative analysis of the apo (a) gene, apo (a) glycoprotein, and plasma concentrations of Lp (a) in three ethnic groups. Evidence for no common" null" allele at the …

A Gaw, E Boerwinkle, JC Cohen… - Journal of Clinical …, 1994 - ncbi.nlm.nih.gov
Distributions of plasma lipoprotein (a)(Lp [a]) concentrations exhibit marked interracial
differences. Apolipoprotein (a)(apo [a]), the unique constituent of Lp (a), is highly …

Differences in Lp [a] concentrations and apo [a] polymorphs between black and white Americans

SM Marcovina, JJ Albers, E Wijsman, Z Zhang… - Journal of lipid …, 1996 - Elsevier
Lp [a] concentrations in nmol/L and apo [a] size isoforms, expressed in terms of the relative
number of apo [a] kringle 4 (K4) repeats, were determined in 3959 whites and blacks from …

Variation in lipoprotein (a) concentration associated with different apolipoprotein (a) alleles.

YF Perombelon, AK Soutar… - The Journal of clinical …, 1994 - Am Soc Clin Investig
Plasma lipoprotein (a)(Lp (a)) concentrations vary considerably between individuals. To
examine the variation for products of the same and different apolipoprotein (a)(apo (a)) …