Human cytomegalovirus infection of human hematopoietic progenitor cells

JP Maciejewski, SC St Jeor - Leukemia & lymphoma, 1999 - Taylor & Francis
For a number of years it has been well established that human Cytomegalovirus (HCMV)
can be transmitted by the cellular components of blood. HCMV is also associated with a …

Spread of human cytomegalovirus (HCMV) after infection of human hematopoietic progenitor cells: model of HCMV latency

T Zhuravskaya, JP Maciejewski… - Blood, The Journal …, 1997 - ashpublications.org
Clinical experience and laboratory data suggest that human cytomegalovirus (HCMV) is
present in peripheral blood of seropositive individuals in a latent or persistent state and can …

Infection of hematopoietic progenitor cells by human cytomegalovirus

JP Maciejewski, EE Bruening, RE Donahue… - 1992 - ashpublications.org
The susceptibility of hematopoietic progenitor cells to infection by human cytomegalovirus
(HCMV) was investigated using several strains of HCMV, including the recombinant strain …

Direct infection of CD34+ progenitor cells by human cytomegalovirus: evidence for inhibition of hematopoiesis and viral replication

M Movassagh, J Gozlan, B Senechal, C Baillou… - 1996 - ashpublications.org
We successfully infected fluorescence-activated cell-sorted CD34+ cells from normal cord
blood by the human cytomegalovirus (HCMV) laboratory strain Towne. An inhibitory effect of …

Human cytomegalovirus replicates in primary human bone marrow cells

H Reiser, J Kühn, HW Doerr… - Journal of general …, 1986 - microbiologyresearch.org
As an attempt to elucidate further the pathogenesis of human cytomegalovirus (HCMV)
infection the replication of HCMV in primary human bone marrow cells (BMC) has been …

Human cytomegalovirus gene expression during infection of primary hematopoietic progenitor cells: a model for latency

FD Goodrum, CT Jordan, K High… - Proceedings of the …, 2002 - National Acad Sciences
Human cytomegalovirus (HCMV) resides latently in hematopoietic cells of the bone marrow.
Although viral genomes can be found in CD14+ monocytes and CD34+ progenitor cells, the …

Infection of blood and bone marrow cells with the human cytomegalovirus in vivo

U Meyer-König, FT Hufert, DM Von Laer - Leukemia & lymphoma, 1997 - Taylor & Francis
The human cytomegalovirus (HCMV) is a major pathogen in immunocompromised patients.
Both, primary infection and reactivation of latent virus can cause disease. Peripheral blood …

Human cytomegalovirus induced inhibition of hematopoietic cell line growth is initiated by events taking place before translation of viral gene products

H Sindre, H Rollag, M Degre, K Hestdal - Archives of virology, 2000 - Springer
Bone marrow suppression with leukopenia is frequently observed during human
cytomegalovirus (HCMV) infection, and in vitro the cell colony formation of bone marrow …

Detection of endogenous human cytomegalovirus in CD34+ bone marrow progenitors

M Mendelson, S Monard… - Journal of General …, 1996 - microbiologyresearch.org
The cellular sites and mechanisms of human cytomegalovirus (HCMV) latency are still
poorly defined. Although evidence suggests that peripheral blood monocytes are one site of …

Human cytomegalovirus infection of the monocyte/macrophage lineage in bone marrow

EJ Minton, C Tysoe, JH Sinclair, JG Sissons - Journal of virology, 1994 - Am Soc Microbiol
Peripheral blood monocytes (PBM) are one site of persistence of human cytomegalovirus
(HCMV) in healthy carriers. However, because PBM circulate only briefly before entering the …