Background Whole genome sequencing (WGS) studies can enhance our understanding of
the role of patients with asymptomatic Clostridium difficile colonization in transmission …

Background It has been thought that Clostridium difficile infection is transmitted
predominantly within health care settings. However, endemic spread has hampered …

Abstract Background. Accurate tracking of Clostridium difficile transmission within healthcare
settings is key to its containment but is hindered by the lack of discriminatory power of …

Background No study has used whole-genome sequencing (WGS) to investigate risk factors
for Clostridium difficile (CD) transmission between cases, or assessed the impact of recent …

No study to date has compared multilocus variable-number tandem-repeat analysis (MLVA)
and whole-genome sequencing (WGS) in an investigation of the transmission of Clostridium …

Abstract Background. Variation in Clostridium difficile infection (CDI) rates between
healthcare institutions suggests overall incidence could be reduced if the lowest rates could …

Background Current approaches in tracking Clostridioides difficile infection (CDI) and
individualizing patient management are incompletely defined. Methods We recruited 468 …

Introduction Combined genotyping/whole genome sequencing and epidemiological data
suggest that in endemic settings only a minority of Clostridium difficile infection, CDI, is …

Summary Background Recurrent Clostridium difficile infection (CDI) represents a significant
healthcare challenge. Patients may suffer multiple episodes of CDI with the index strain …

Understanding the contribution of relapse and reinfection to recurrent Clostridium difficile
infection (CDI) has implications for therapy and infection prevention, respectively. We used …