[HTML][HTML] Incretins and cardiovascular disease: to the heart of type 2 diabetes?

A Solini, D Tricò, S Del Prato - Diabetologia, 2023 - Springer
Major cardiovascular outcome trials and real-life observations have proven that glucagon-
like peptide-1 (GLP-1) receptor agonists (GLP-1RAs), regardless of structural GLP-1 …

Cardiovascular effects of incretin-based therapies: integrating mechanisms with cardiovascular outcome trials

JR Ussher, AA Greenwell, MA Nguyen, EE Mulvihill - Diabetes, 2022 - Am Diabetes Assoc
As the worldwide prevalence of diabetes and obesity continues to rise, so does the risk of
debilitating cardiovascular complications. Given the significant association between …

Harnessing the incretin system beyond glucose control: potential cardiovascular benefits of GLP-1 receptor agonists in type 2 diabetes

B Cariou - Diabetes & metabolism, 2012 - Elsevier
The management of type 2 diabetes continues to evolve as new data emerge. Although
glycaemic control is still important, other risk factors–such as hypertension, dyslipidaemia …

The effect of glucagon-like peptide 1 on cardiovascular risk

J Sivertsen, J Rosenmeier, JJ Holst… - Nature Reviews …, 2012 - nature.com
Abstract Glucagon-like peptide 1 (GLP-1) is an incretin hormone responsible for
amplification of insulin secretion when nutrients are given orally, as opposed to …

Cardiovascular biology of the incretin system

JR Ussher, DJ Drucker - Endocrine reviews, 2012 - academic.oup.com
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that enhances glucose-stimulated
insulin secretion and exerts direct and indirect actions on the cardiovascular system. GLP-1 …

Cardiovascular protective properties of incretin-based therapies in type 2 diabetes

S Simsek, BE de Galan - Current opinion in lipidology, 2012 - journals.lww.com
Cardiovascular protective properties of incretin-based thera... : Current Opinion in Lipidology
Cardiovascular protective properties of incretin-based therapies in type 2 diabetes : Current …

The incretin system and cardiovascular risk: Effects of incretin-targeted therapies

D Mundil, MH Noyan-Ashraf, M Husain - Current Cardiovascular Risk …, 2011 - Springer
Incretins, such as glucagon-like peptide-1 (GLP-1), are gut peptides that stimulate insulin
secretion. Incretin-targeted therapeutics for type 2 diabetes include both direct GLP-1 …

GLP-1 receptor agonists and atherosclerosis protection: the vascular endothelium takes center stage

B Park, E Bakbak, H Teoh… - American Journal …, 2024 - journals.physiology.org
Atherosclerotic cardiovascular disease is a chronic condition that often copresents with type
2 diabetes and obesity. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are incretin …

The incretin system and cardiometabolic disease

PE Szmitko, LA Leiter, S Verma - Canadian Journal of Cardiology, 2010 - Elsevier
Rates of type 2 diabetes, obesity and their associated detrimental cardiovascular effects are
rapidly increasing. Despite the availability of several treatment options for type 2 diabetes …

[HTML][HTML] Incretin-based therapies: can we achieve glycemic control and cardioprotection?

FS Angeli, RP Shannon - Journal of Endocrinology, 2014 - joe.bioscientifica.com
Abstract Glucagon-like (GLP-1) is a peptide hormone secreted from the small intestine in
response to nutrient ingestion. GLP-1 stimulates insulin secretion in a glucose-dependent …