The adenosine receptors (ARs) in the nervous system act as a kind of “go-between” to
regulate the release of neurotransmitters (this includes all known neurotransmitters) and the …

Adenosine receptors (ARs) are a class of G-protein coupled receptors (GPCRs) that are
activated by the endogenous substance adenosine. ARs are classified into 4 subtype …

Since the discovery of the biological effects of adenosine, the development of potent and
selective agonists and antagonists of adenosine receptors has been the subject of medicinal …

The expression of the human adenosine A2A receptor was examined by reverse
transcription polymerase chain reaction in post-mortem human brain tissue that was …

Adenosine acts as a neuromodulator through at least two receptor subtypes, A 1 and A 2. A
2 receptors have been further divided into A 2A (high agonist affinity) and A 2B (low agonist …

A putative A4 adenosine receptor is characterized by a distinct structure activity profile of
compounds in competition for [3H] 2-phenylaminoadenosine ([3H] CV 1808) binding sites …

* Address correspondence to: PJM van Galen, NIH/NIDDK, Building 8A, Room B1A-17,
Bethesda, MD 20892; telephone 301-496-9024; fax 301-402-0008. Medicinal Research …

A novel receptor cDNA was isolated from a human hippocampal cDNA library. The encoded
polypeptide contains structural features consistent with its classification as a G protein …

Adenosine A2A receptors are highly concentrated in the striatum, where they play an
important modulatory role of glutamatergic transmission to the GABAergic enkephalinergic …

The A 2a adenosine receptor, a member of the G protein-coupled receptor family, is
important in the regulation of dopaminergic pathways of the brain and in platelet and …