Rationale A few recent studies suggest that brain histamine levels and signaling via H 3
receptors play an important role in modulation of alcohol stimulation and reward in rodents …

Histamine H3 receptor (H3R) antagonists are currently being investigated for the possible
therapeutic use in various cognitive deficits such as those in schizophrenia, attention deficit …

Rationale Neuronal histamine has a prominent role in sleep–wake control and body
homeostasis, but a number of studies suggest that histamine has also a role in higher brain …

Histamine H3 receptors (H3Rs) are presynaptic receptors that negatively regulate the
release of histamine. The present study examined the physiological role of H3Rs in drinking …

Brain histamine H3 receptors are predominantly presynaptic and serve an important
autoregulatory function for the release of histamine and other neurotransmitters. They have …

Recent studies suggest that the brain histaminergic system and especially the H3 receptors
are involved in the regulation of alcohol consumption and alcohol-induced behaviors. Part of …

Histamine H3 receptors were first described in the eighties but finally cloned four years ago.
They are G-protein coupled, mostly presynaptic, and are involved in the control of the …

The histamine H 3 receptor is an attractive G protein–coupled receptor drug target that
regulates neurotransmission in the central nervous system and plays a role in cognitive and …

Abstract Histamine H 3 receptors (H 3 R) are widely expressed in the brain where they
participate in sleep–wake cycle and cognition among other functions. Despite their high …

Abstract Histamine H1 receptor (H1R) in the central nervous system plays an important role
in various functions, including learning and memory, aggression, feeding behaviors, and …