Chronic hepatitis B virus (HBV) infection continues to be a major health problem worldwide
and remains hard to be cured. Therapy with interferon (IFN) α is an important method for the …

Interferon alpha (IFNα) is commonly used for the treatment of chronic hepatitis B (CHB)
patients. There are 13 different IFNα subtypes in humans, but only the subtype IFNα2 is used …

Interferons α and β (IFNα and IFNβ) are type I interferons produced by the host to control
pathogen propagation. However, only a minority of chronic hepatitis B (CHB) patients …

Background and Aims Interferon (IFN)‐α, composed of numerous subtypes, plays a crucial
role in immune defense. As the most studied subtype, IFN‐α2 has been used for treating …

Fritz Lai, mdcflsc@ nus. edu. sg Yang Wang, 596868170@ qq. com Kathrin Sutter, kathrin.
sutter@ uni-due. de Ulf Dittmer, ulf. dittmer@ uni-due. de Jianyu Ye, 14301010010@ fudan …

During most viral infections, the immediate host response is characterized by an induction of
type I IFN. These cytokines have various biological activities, including anti‐viral, anti …

It remains controversial how interferon (IFN) response contributes to hepatitis B virus (HBV)
control and pathogenesis. A previous study identified that hydrodynamic injection (HI) of …

Objectives Dissecting the underlying mechanism of T cells remodeling mediated by
interferon α (IFN-α) is indispensable for achieving an optimum therapeutic response in …

About 0.8 million people die because of hepatitis B virus (HBV) infection each year. In
around 5% of infected adults, the immune system is ineffective in countering HBV infection …

HBV infection remains a leading cause of death worldwide. IFN-α inhibits viral replication in
vitro and in vivo, and pegylated IFN-α is a commonly administered treatment for individuals …