NRF2 (Nuclear factor E2 p45‐related factor 2) is a stress responsive transcription factor
lending cells resilience against oxidative, xenobiotic, and also nutrient or proteotoxic insults …

In light of the emerging interplay between redox and metabolic signaling pathways we
investigated the potential cross talk between nuclear factor E2-related factor 2 (Nrf2) and …

The transcription factor Nrf2 (nuclear factor (erythroid-derived 2)-like 2) and the kinase
AMPK (AMP-activated protein kinase) participate in the cellular adaptive response to redox …

Since eukaryotic cells constantly encounter various environmental insults, they have
evolved defense mechanisms to cope with toxicant-and carcinogen-induced oxidative stress …

The bZIP transcription factor Nrf2 has emerged as a pivotal regulator of intracellular redox
homeostasis by controlling the expression of many endogenous antioxidants and phase II …

Nrf2, a redox sensitive transcription factor, plays a pivotal role in redox homeostasis during
oxidative stress. Nrf2 is sequestered in cytosol by an inhibitory protein Keap1 which causes …

The Keap1–Nrf2 pathway plays a crucial role in determining the sensitivity of cells to
chemical and/or oxidative insults by regulating the basal and inducible expression of …

The Nrf2 transcription factor governs the expression of hundreds genes involved in cell
defense against oxidative stress, the hallmark of numerous diseases such as …

The redox regulator NRF2 becomes activated upon oxidative and electrophilic stress and
orchestrates a response program associated with redox regulation, metabolism, tumor …

Significance: The nuclear factor erythroid 2-related factor 2 (NRF2)-Kelch-like ECH-
associated protein 1 (KEAP1) system is a master regulator of redox homeostasis and cell …