Nrf2 (nuclear factor erythroid 2-related factor 2) is an antioxidant transcription factor. AMP-
activated protein kinase (AMPK) functions as a central regulator of cell survival in response …

Significance: Inflammation can be defined as a protective immune response against harmful
exogenous and endogenous stimuli. Nevertheless, prolonged or autoimmune inflammatory …

Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that regulates the
cellular defense against toxic and oxidative insults through the expression of genes involved …

Nutritional status provides metabolic substrates to activate AMP-Activated Protein Kinase
(AMPK), the energy sensor that regulates metabolism. Recent evidence has demonstrated …

The coordinating role of nuclear factor erythroid-2-related factor 2 (Nrf2) in cellular function
is undeniable. Evidence indicates that this transcription factor exerts massive regulatory …

Simple Summary The stress-responsive transcription factor NRF2 (nuclear factor-erythroid 2
p45-related factor 2) directs cellular metabolic processes that can have diverse effects in the …

Oxidative stress, a term that describes the imbalance between oxidants and antioxidants,
leads to the disruption of redox signals and causes molecular damage. Increased oxidative …

In the broadest sense, cellular stress describes conditions wherein cells encounter and react
to a 'non-normal'state. Perturbations may originate through both extracellular and …

AMPK (AMP-activated protein kinase) is one of the key players in maintaining intracellular
homoeostasis. AMPK is well known as an energy sensor and can be activated by increased …

A wide array of dietary phytochemicals have been reported to induce the expression of
enzymes involved in both cellular antioxidant defenses and elimination/inactivation of …