Leveraging Aptamer-Based DNA Nanotechnology for Bioanalysis and Cancer Therapeutics
Conspectus Aptamers are single-stranded DNA or RNA molecules composed of 15–80
nucleotides, obtained from a random oligonucleotide library via the systematic evolution of …
nucleotides, obtained from a random oligonucleotide library via the systematic evolution of …
Integrating DNA nanotechnology with aptamers for biological and biomedical applications
Z Huang, L Qiu, T Zhang, W Tan - Matter, 2021 - cell.com
In addition to critical biological roles, DNA is also considered an excellent engineering
material with unique characteristics of high programmability and addressability. Recent …
material with unique characteristics of high programmability and addressability. Recent …
Current advances in aptamers for cancer diagnosis and therapy
Nucleic acid aptamers are single-stranded oligonucleotides that interact with target
molecules with high affinity and specificity in unique three-dimensional structures. Aptamers …
molecules with high affinity and specificity in unique three-dimensional structures. Aptamers …
Nucleic acid aptamers in cancer research, diagnosis and therapy
Aptamers are single-stranded DNA or RNA oligomers, identified from a random sequence
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …
Aptamer-based probes for cancer diagnostics and treatment
X Hu, D Zhang, Z Zeng, L Huang, X Lin, S Hong - Life, 2022 - mdpi.com
Aptamers are single-stranded DNA or RNA oligomers that have the ability to generate
unique and diverse tertiary structures that bind to cognate molecules with high specificity. In …
unique and diverse tertiary structures that bind to cognate molecules with high specificity. In …
Aptamers: Promising Reagents in Biomedicine Application
H Zhou, Y Li, W Wu - Advanced Biology, 2024 - Wiley Online Library
Nucleic acid aptamers, often termed “chemical antibodies,” are short, single‐stranded DNA
or RNA molecules, which are selected by SELEX. In addition to their high specificity and …
or RNA molecules, which are selected by SELEX. In addition to their high specificity and …
Materials applications of aptamers
Aptamers are a class of functional oligonucleotides that are in vitro selected via systematic
evolution of ligands by exponential enrichment (SELEX). Aptamers can bind a wide range of …
evolution of ligands by exponential enrichment (SELEX). Aptamers can bind a wide range of …
DNA aptamer technology for personalized medicine
Highlights•The development of DNA aptamers parallels that of personalized medicine.•Both
aptamer-functionalized nanomaterials and DNA nanostructures have been developed.•They …
aptamer-functionalized nanomaterials and DNA nanostructures have been developed.•They …
DNA aptamer based nanodrugs: molecular engineering for efficiency
In the past two decades, the study of cancer therapy has gradually advanced to the “nano”
era. Numerous novel nanomaterials armed with unique physical properties have been …
era. Numerous novel nanomaterials armed with unique physical properties have been …
[HTML][HTML] Aptamer-enabled nanomaterials for therapeutics, drug targeting and imaging
A wide variety of nanomaterials have emerged in recent years with advantageous properties
for a plethora of therapeutic and diagnostic applications. Such applications include drug …
for a plethora of therapeutic and diagnostic applications. Such applications include drug …