Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists

P Picard, D Regoli, R Couture - British journal of pharmacology, 1994 - Wiley Online Library
1 The effects of intracerebroventricular (icv) injection of selective and potent NK1 (RP
67580), NK2 (SR 48968) and NK3 (R 486,[Trp7, β‐Ala8] NKA (4–10)) receptor antagonists …

Use of selective antagonists to dissociate the central cardiovascular and behavioural effects of tachykinins on NK1 and NK2 receptors in the rat.

C Tschöpe, P Picard, J Culmann, A Prat… - British journal of …, 1992 - ncbi.nlm.nih.gov
The effects of intracerebroventricular (icv) pretreatment with selective NK1 ((+/-)-CP 96,345),
NK2a (MEN 10,207; MEN 10,376) and NK2b (R 396) tachykinin receptor antagonists on the …

Effects of the tachykinin NK1 receptor antagonist, RP 67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B

J Culman, B Wiegand, H Spitznagel… - British journal of …, 1995 - Wiley Online Library
1 We have investigated the effects of the non‐peptide NK1 tachykinin receptor antagonist,
RP 67580, and its inactive enantiomer, RP 68651, on the cardiovascular and behavioural …

Cardiovascular and behavioural effects of centrally administered neuropeptide K in the rat: receptor characterization

A Prat, P Picard, R Couture - British journal of pharmacology, 1994 - Wiley Online Library
1 The cardiovascular and behavioural responses to intracerebroventricularly (icv)
administered neuropeptide K (NPK) were studied in conscious rats. The central effects of …

Cardiovascular and behavioural effects of intracerebroventricularly administered tachykinin NK3 receptor antagonists in the conscious rat

E Cellier, L Barbot, D Regoli… - British journal of …, 1997 - Wiley Online Library
1 In the conscious rat, three tachykinin NK3 receptor antagonists, namely SR142801 ((S)‐
(N)‐(1‐(3‐(1‐benzoyl‐3‐(3, 4‐dichlorophenyl) piperidin‐3‐yl) propyl)‐4‐phenylpiperidin‐4 …

Modulation of cardiac activity by tachykinins in the rat substantia nigra

A Lessard, R Couture - British journal of pharmacology, 2001 - Wiley Online Library
The effects of tachykinin NK1, NK2 and NK3 receptor agonists and antagonists were
measured on blood pressure (MAP) and heart rate (HR) after bilateral microinjection into the …

Study of SR 142801, a new potent non‐peptide NK3 receptor antagonist on cardiovascular responses in conscious guinea‐pig

A Roccon, D Marchionni… - British journal of …, 1996 - Wiley Online Library
1 The cardiovascular responses to intravenous (iv) injection of natural tachykinins,
substance P (SP), neurokinin A (NKA), neurokinin B (NKB) and selective tachykinin (NK) …

Functional interaction between losartan and central tachykinin NK3 receptors in the conscious rat

P Picard, L Chretien, R Couture - British journal of …, 1995 - Wiley Online Library
1 The cardiovascular and behavioural effects elicted by the intracerebroventricular (icv)
injection of substance P (SP), neurokinin A (NKA),[MePhe7] neurokinin B ([MePhe7] NKB) or …

Comparative behavioural profile of centrally administered tachykinin NK1, NK2 and NK3 receptor agonists in the guinea‐pig

O Piot, J Betschart, I Grall, S Ravard… - British journal of …, 1995 - Wiley Online Library
1 The NK, tachykinin receptor agonists, septide,[Sar9, Met (O2) 11] SP and [Pro9] SP
produced locomotor hyperactivity (10–20 min) when injected intracerebroventricularly (icv) …

The ventral tegmental area as a putative target for tachykinins in cardiovascular regulation

K Deschamps, R Couture - British journal of pharmacology, 2005 - Wiley Online Library
1 Tachykinin receptor agonists and antagonists were microinjected into the ventral
tegmental area (VTA) to study the relative participation of the three tachykinin receptors in …