Alzheimer's disease is a chronic and progressive brain neurodegenerative disease affecting
over 30 million people globally. Currently, no effective treatment is available due to multiple …

Alzheimer's disease (AD) is a progressive multifactorial neurodegenerative disorder.
Currently, no effective treatment is available and this is due to multiple factors involved in …

Alzheimer's disease (AD) is the most common form of dementia affecting specifically older
population. AD is an irreversible neurodegenerative CNS disorder associated with complex …

The discovery and development of multitarget-directed ligands (MTDLs) is a promising
strategy to find new therapeutic solutions for neurodegenerative diseases (NDs), in …

Alzheimer's disease (AD) is a complex neurodegenerative disorder with a multi-faceted
pathogenesis. So far, the therapeutic paradigm “one-compound-one-target” has failed and …

Among the various drug discovery methods, a very promising modern approach consists in
designing multi-target-directed ligands (MTDLs). This methodology has been specifically …

To determine chemical–protein interactions (CPI) is costly, time-consuming, and labor-
intensive. In silico prediction of CPI can facilitate the target identification and drug discovery …

Alzheimer's disease (AD) is a multifactorial syndrome resulting in profound misery and
poses a substantial burden on human health, economy, and society throughout the world …

Alzheimer's disease (AD) is a multifactorial irreversible neurological disorder which results
in cognitive impairment, loss of cholinergic neurons in synapses of the basal forebrain and …

With 27 million cases worldwide documented in 2006, Alzheimer's disease (AD) constitutes
an overwhelming health, social, economic, and political problem to nations. Unless a new …