Central apnea, defined as cessation of breathing for≥ 20 s, is frequent in premature infants
born at< 34 weeks׳ gestation but uncommon among healthy late preterm (34 0/7–36 6/7 …

OBJECTIVE: Apnea of prematurity (AoP) is, in part, a reflection of brainstem-mediated
respiratory control system maturation. We previously demonstrated changes in brainstem …

Objective To evaluate whether jaundice, indexed by unbound bilirubin (UB), is associated
with central apnea in premature infants. Study design A prospective observational study was …

Hyperbilirubinemia is the most common clinical condition requiring evaluation and treatment
in the newborn [1] and the most common cause for hospital readmission during the first …

Objective: To describe and compare infants with severe hyperbilirubinemia, who presented
with and without abnormal neurological findings and to identify associated risk factors. Study …

Although hyperbilirubinemia affects most term and late preterm infants in the immediate
postnatal period, it is generally modest and of little clinical significance. 1 However, a subset …

The immature hepatic metabolism of bilirubin at birth is responsible for neonatal
hyperbilirubinemia, present in more than 60% of otherwise healthy infants. Icterus (or …

Before the 1994 recommendations of the AAP for the US population (1), the pediatric
literature was replete with articles on a kinder, gentler demedicalized management of …

Chronic bilirubin encephalopathy, characterized clinically by extrapyramidal movement
abnormalities, vertical gaze abnormalities, and hearing loss, results from neuronal injury …

Although apnea is common in premature babies, there is a paucity of information concerning
the pathophysiologic basis of these episodes and their relationship to other perinatal …