[PDF][PDF] Omental milky spots develop in the absence of lymphoid tissue-inducer cells and support B and T cell responses to peritoneal antigens

J Rangel-Moreno, JE Moyron-Quiroz, DM Carragher… - Immunity, 2009 - cell.com
The omentum is a site of B1 cell lymphopoiesis and immune responsiveness to T cell-
independent antigens. However, it is unknown whether it supports immune responses …

Morpho-physiological function and role of omental milky spots as omentum-associated lymphoid tissue (OALT) in the peritoneal cavity

M Shimotsuma, JW Shields… - …, 1993 - journals.uair.arizona.edu
The morpho-physiological function and role of milky spots in the greater omentum are
reviewed. These milky spots are composed of cellular aggregations of mesenchymal cells …

[PDF][PDF] Lymphoid organs for peritoneal cavity immune response: milky spots

RE Mebius - Immunity, 2009 - cell.com
Lymphoid Organs for Peritoneal Cavity Immune Response: Milky Spots Page 1 autoimmune
or autoaggressive disease. The new climax of research on Perforin, as reported here, may …

Biodefense function of omental milky spots through cell adhesion molecules and leukocyte proliferation

L Cui, K Johkura, Y Liang, R Teng, N Ogiwara… - Cell and tissue …, 2002 - Springer
To evaluate the immunological functions of the greater omentum in the peritoneal cavity, the
localization of cell adhesion molecules (CAMs) on mesothelial cells and leukocytes in the …

Omental milky spots in the local immune response in the peritoneal cavity of rats

E Van Vugt, EAM Van Rijthoven… - … Record: An Official …, 1996 - Wiley Online Library
Background Milky spots have been described as reactive structures, their classification
varying from inflamed or haematopoietic tissue to lymphoid organs. In this study we …

Lymphocytes in the peritoneum home to the omentum and are activated by resident dendritic cells

DA Carlow, MR Gold, HJ Ziltener - The Journal of Immunology, 2009 - journals.aai.org
The omentum is of interest in the context of obesity-related metabolic disease where
adipose tissue exhibits inflammatory changes; however, the immunology of the omentum is …

Specialized immune responses in the peritoneal cavity and omentum

M Liu, A Silva-Sanchez, TD Randall… - Journal of Leucocyte …, 2021 - academic.oup.com
The peritoneal cavity is a fluid filled space that holds most of the abdominal organs,
including the omentum, a visceral adipose tissue that contains milky spots or clusters of …

Development of Peyer's patches, follicle-associated epithelium and M cell: lessons from immunodeficient and knockout mice

N Debard, F Sierro, JP Kraehenbuhl - Seminars in immunology, 1999 - Elsevier
Studies with immunodeficient and knockout mice have re-vealed that the development of
mucosa-associated lymphoid tissues (MALT) and peripheral lymphoid nodes share com …

Organogenesis of peripheral lymphoid organs

SI Nishikawa, K Honda, P Vieira… - Immunological …, 2003 - Wiley Online Library
The discovery that lymphotoxin α (LTα) knockout mice lack peripheral lymphoid tissues
reformed the study of organogenesis of peripheral lymphoid tissues from a research field …

Differential molecular and anatomical basis for B cell migration into the peritoneal cavity and omental milky spots

S Berberich, S Dähne, A Schippers… - The Journal of …, 2008 - journals.aai.org
The constitutive migration of B cells from the circulation into the peritoneal cavity and back is
essential for peritoneal B cell homeostasis and function. However, the molecular machinery …