Alveolar oxygen partial pressure and oxygen depletion rate mapping in rats using 3He ventilation imaging

K Cieślar, V Stupar, E Canet‐Soulas… - … in Medicine: An …, 2007 - Wiley Online Library
A hyperpolarized 3He ventilation imaging protocol was implemented to assess alveolar pO2
values and the oxygen depletion rate in rats. The imaging protocol, which is based on spiral …

Improved technique for measurement of regional fractional ventilation by hyperpolarized 3He MRI

K Emami, SJ Kadlecek, JM Woodburn… - … in Medicine: An …, 2010 - Wiley Online Library
Quantitative measurement of regional lung ventilation is of great significance in assessment
of lung function in many obstructive and restrictive pulmonary diseases. A new technique for …

3He MRI in healthy volunteers: preliminary correlation with smoking history and lung volumes

D Guenther, B Eberle, J Hast, J Lill… - NMR in Biomedicine …, 2000 - Wiley Online Library
Abstract MRI with hyperpolarized helium‐3 (3He) provides high‐resolution imaging of
ventilated airspaces. The first aim of this 3He‐study was to compare observations of …

Emphysema Index Based on Hyperpolarized 3He or 129Xe Diffusion MRI: Performance and Comparison with Quantitative CT and Pulmonary …

S Tafti, WJ Garrison, JP Mugler III, YM Shim, TA Altes… - Radiology, 2020 - pubs.rsna.org
Background Apparent diffusion coefficient (ADC) maps of inhaled hyperpolarized gases
have shown promise in the characterization of emphysema in patients with chronic …

Proton magnetic resonance imaging for assessment of lung function and respiratory dynamics

M Eichinger, R Tetzlaff, M Puderbach… - European journal of …, 2007 - Elsevier
Since many pulmonary diseases present with a variable regional involvement, modalities for
assessment of regional lung function gained increasing attention over the last years …

Influence of oxygen flow rate on signal and T1 changes in oxygen‐enhanced ventilation imaging

VM Mai, B Liu, W Li, J Polzin, S Kurucay… - Journal of Magnetic …, 2002 - Wiley Online Library
Purpose To investigate the optimal oxygen flow rate for oxygen‐enhanced MR ventilation
imaging. Materials and Methods Using a cardiac‐triggered nonselective inversion recovery …

Quantitative mapping of ventilation‐perfusion ratios in lungs by 19F MR imaging of T1 of inert fluorinated gases

NL Adolphi, DO Kuethe - … in Medicine: An Official Journal of the …, 2008 - Wiley Online Library
A new method is presented for quantitative mapping of ventilation‐to‐perfusion ratios (VA/Q)
in the lung: MRI of the 19F longitudinal relaxation time (T1) of an inert fluorinated gas at …

Breath‐hold 3D gradient‐echo MR imaging of the lung parenchyma: Evaluation of reproducibility of image quality in normals and preliminary observations in patients …

RC Semelka, NC Balci, KP Wilber… - Journal of Magnetic …, 2000 - Wiley Online Library
This study evaluates the reproducibility and image quality of a three‐dimensional (3D)
gradient‐echo sequence for imaging the lung parenchyma, with and without gadolinium …

Reproducibility of spirometrically controlled CT lung densitometry in a clinical setting

RJ Lamers, GJ Kemerink, M Drent… - European …, 1998 - Eur Respiratory Soc
The aim of this study was to assess the reproducibility of quantitative, spirometrically gated
computed tomographic (CT) lung densitometry at defined levels of inspiration in hospitalized …

Quantitative in vivo assessment of lung microstructure at the alveolar level with hyperpolarized 3He diffusion MRI

DA Yablonskiy, AL Sukstanskii… - Proceedings of the …, 2002 - National Acad Sciences
The study of lung emphysema dates back to the beginning of the 17th century. Nevertheless,
a number of important questions remain unanswered because a quantitative localized …